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Impact of psychiatric disorders on pregnancy and its management. A French retrospective cohort study

Published online by Cambridge University Press:  19 July 2023

E. Briaud ,
D. Doolub ,
S. Guinot ,
J. Deparis  and
N. Jaafari
E. Briaud
Affiliation:
Ecole de Sages-Femmes, Faculté de médecine et de pharmacie de Poitiers, CHU de Poitiers
D. Doolub*
Affiliation:
Experimental psychology, CNRS, Université de Poitiers, Université de Tours, CeRCA, Poitiers, France Neuromodulation and Adult Psychiatry, Pierre Deniker Research Center
S. Guinot
Affiliation:
Ecole de Sages-Femmes, Faculté de médecine et de Pharmacie de Poitiers, Centre Hospitalier Universitaire de Poitiers, Poitiers, France
J. Deparis
Affiliation:
Ecole de Sages-Femmes, Faculté de médecine et de Pharmacie de Poitiers, Centre Hospitalier Universitaire de Poitiers, Poitiers, France
N. Jaafari
Affiliation:
Experimental psychology, CNRS, Université de Poitiers, Université de Tours, CeRCA, Poitiers, France Neuromodulation and Adult Psychiatry, Pierre Deniker Research Center
*
*Corresponding author.

Abstract

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Introduction

Every pregnancy and birth is unique, and despite this, few studies exist on the condition of pregnant women with mental disorders.

Objectives

This study analyzes the impact of prevalent mental disorders in pregnant women to determine which clinical or socio-demographic characteristics significantly impact pregnancy.

Methods

This retrospective and naturalistic cohort study is based on the medical records of 99 patients managed in a university hospital. All patients had an ICD-10 mental disorder (psychiatric and/or substance use disorders) diagnosed before pregnancy.

Results

Only 24.2% of the pregnant women had no adverse outcomes throughout pregnancy, labor, and delivery. The remaining mothers had violence issues, and mothers with psychotrauma were likelier to have stillborn babies. Pregnant women with mental disorders were less keen to screen for Down’s syndrome and more likely to have artificial delivery in case of comorbid drug addiction and alcohol use disorder (AUD). Anonymous birth and placement of newborns were related to substance abuse and pre-pregnancy AUD comorbidities or AUD alone before pregnancy. Besides, four clinical characteristics were found to be predictive of adverse pregnancy outcomes: young maternal age (β=-1,15,p<.03), late-term first contact with the maternity hospital (β=0.08,p<.02), advanced term of delivery (β=4.01,p<.03), and a history of psychiatric disorders associated with an AUD but without smoking before pregnancy (β=-1,07,p<.03). Despite all, pregnant women had a relatively sustained follow-up of their pregnancies.

Conclusions

Mental disorders have a negative impact on pregnancy. More studies should be promoted to raise the attention of professionals to manage and improve women’s pregnancy and motherhood with psychiatric conditions.

Disclosure of Interest

None Declared

Type
Abstract
Information
European Psychiatry , Volume 66 , Special Issue S1: Abstracts of the 31st European Congress of Psychiatry , March 2023 , pp. S650 - S651
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2023. Published by Cambridge University Press on behalf of the European Psychiatric Association
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