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Gender differences in the association of dementia and depression

Published online by Cambridge University Press:  27 August 2024

R. Fernández Fernández ,
P. del Sol Calderón  and
Á. Izquierdo de la Puente
R. Fernández Fernández*
Affiliation:
1Psychiatry, Hospital Universitario Infanta Cristina, Parla
P. del Sol Calderón
Affiliation:
2Psychiatry, Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Spain
Á. Izquierdo de la Puente
Affiliation:
2Psychiatry, Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Spain
*
*Corresponding author.

Abstract

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Introduction

The evolution of depression and dementia has been shown to differ in some studies. For example, a history of recent depression has been found to be associated with an increased risk of Alzheimer’s disease in women (Kim et al., 2021).

Objectives

We will use data collected from several dementia studies to analyze whether the presence of depression at diagnosis is more frequent in women.

Methods

We conducted a systematic search for articles analyzing the presence of depression in patients with a diagnosis of dementia. We analyzed by Student’s t test the presence of depression according to sex, considering the alternative hypothesis that there is more depression in female than male patients.

Results

The mean age of the sample was 71 years. We obtained a statistically significant Student’s t test (p=0.02).

Conclusions

The approach and approach to depression in the elderly as a risk factor could be different according to sex. For example, some studies have proposed the use of hormone replacement therapy (HRT) after menopause as a possible protective factor for the subsequent development of dementia (Kim et al., 2022). Further studies are recommended in this regard.

Disclosure of Interest

None Declared

Type
Abstract
Information
European Psychiatry , Volume 67 , Special Issue S1: Abstracts of the 32nd European Congress of Psychiatry , April 2024 , pp. S640 - S641
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of European Psychiatric Association
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