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Functional hemisphere imbalance in patients with paranoid or disorganized schizophrenia

Published online by Cambridge University Press:  16 April 2020

B Spivak ,
N Karny ,
G Katz ,
M Radwan ,
A Apter ,
R Master  and
A Weizman
B Spivak
Affiliation:
Research Unit, Ness Ziona Mental Health Center, Ness Ziona and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv
N Karny
Affiliation:
Research Unit, Ness Ziona Mental Health Center, Ness Ziona and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv
G Katz
Affiliation:
Eytanim Psychiatric Hospital, Jerusalem
M Radwan
Affiliation:
Research Unit, Geha Psychiatric Hospital, Beilinson Medical Center, Petah Tiqva
A Apter
Affiliation:
Research Unit, Geha Psychiatric Hospital, Beilinson Medical Center, Petah Tiqva
R Master
Affiliation:
Research Unit, Ness Ziona Mental Health Center, Ness Ziona and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv
A Weizman*
Affiliation:
Research Unit, Geha Psychiatric Hospital, Beilinson Medical Center, Petah Tiqva Geha Psychiatric Hospital and Felsenstein Medical Research Center, Beilinson Medical Center, Petah Tiqva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
*
*Correspondence and reprints: A Weizman, Laboratory of Biological Psychiatry, Felsenstein Medical Research Center, c/o Beilinson Medical Center, Petah Tiqva 49100, Israel.
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Summary

We assessed hemisphere function in right-handed male chronic schizophrenic patients using dichotic listening tests. We evaluated digit, tonic and transitional tests in patients with paranoid schizophrenia (n = 8), patients with disorganized schizophrenia (n = 8) and in control subjects (n = 8). The dichotic listening analysis discriminated between paranoid and disorganized schizophrenia. In disorganized schizophrenia, functional impairment of both hemispheres was demonstrated, while in paranoid schizophrenia dysfunction was more prominent in the right hemisphere. These results indicate the possible involvement of right hemisphere dysfunction in the pathophysiology of chronic paranoid schizophrenia, in contrast to dysfunction of both hemispheres in chronic disorganized schizophrenia.

Keywords

dichotic listeningschizophrenic patientshemispheric function
Type
Original article
Information
European Psychiatry , Volume 11 , Issue 4 , 1996 , pp. 175 - 179
Copyright
Copyright © Elsevier, Paris 1996

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