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Fibromyalgia and Cannabinoids: Emerging Issues

Published online by Cambridge University Press:  16 April 2020

N. Madeira ,
J. Cerejeira ,
C. Miguel ,
M. Matos ,
S. Santo ,
P. Carriço  and
M.J. Quartilho
N. Madeira
Affiliation:
Psychiatric Clinic, Coimbra University Hospital, Coimbra, Portugal
J. Cerejeira
Affiliation:
Psychiatric Clinic, Coimbra University Hospital, Coimbra, Portugal
C. Miguel
Affiliation:
Psychiatric Clinic, Coimbra University Hospital, Coimbra, Portugal
M. Matos
Affiliation:
Psychiatric Clinic, Coimbra University Hospital, Coimbra, Portugal
S. Santo
Affiliation:
Psychiatric Clinic, Coimbra University Hospital, Coimbra, Portugal
P. Carriço
Affiliation:
Psychiatric Clinic, Coimbra University Hospital, Coimbra, Portugal
M.J. Quartilho
Affiliation:
Psychiatric Clinic, Coimbra University Hospital, Coimbra, Portugal

Abstract

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Fibromyalgia is a chronic disorder characterized by widespread and long-lasting pain, tenderness, and fatigue. It is associated with impaired quality of life, and significant social and health burden.

The etiopathogenesis of this condition is presently undefined, but is probably multifactorial. The hypothesis of a clinical endocannabinoid deficiency has been proposed. In fact, recent studies suggest that synthetic cannabinoids might be an effective therapy in patients with fibromyalgia.

Based on the clinical case of a female patient whose cannabis use was related to symptomatic relief of fibromyalgia, the authors review issues concerning the endocannabinoid system, its possible relation to this challenging pain disorder, and therapeutic possibilities with synthetic cannabinoids.

Type
P02-251
Information
European Psychiatry , Volume 24 , Issue S1: 17th EPA Congress - Lisbon, Portugal, January 2009, Abstract book , January 2009 , 24-E941
Copyright
Copyright © European Psychiatric Association 2009
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