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Emotional deficit: an adaptative and evolutive process in HIV infection

Published online by Cambridge University Press:  16 April 2020

C Bungener ,
JJ Lefrère ,
D Widlöcher  and
R Jouvent
C Bungener
Affiliation:
CNRS URA 1957, Hôpital de la Salpêtrière, 47 bd de l’Hôpital, 75013Paris
JJ Lefrère
Affiliation:
Service Médecine Interne, Hôpital Saint-Antoine, Paris
D Widlöcher
Affiliation:
INSERM 302, Hôpital de la Salpêtrière, Paris, France
R Jouvent
Affiliation:
CNRS URA 1957, Hôpital de la Salpêtrière, 47 bd de l’Hôpital, 75013Paris
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Summary

The objective of the present study was to evaluate emotional disturbances and psychopathological symptoms in early stages of human immunodeficiency virus (HIV) infection. Seventy-one homosexual subjects, positive to HIV and two groups of HIV-negative subjects (32 homosexuals and 26 heterosexuals) were evaluated in a semi-structured interview by two trained raters. The results showed the presence of emotional perturbations already in asymptomatic HIV-positive individuals even in the absence of caracterized depression and/or anxiety. This emotional deficit seemed to be more important in more advanced stages of the disease. Depressive and anxious symptoms appeared to be slightly but significantly present in both groups of homosexual men. This emotional deficit could be the reflect of an adaptative process to the threatening consequences of HIV-infection. Emotional perturbations, even mild should not be neglected, because their reduction contributes to the psychological well being of HIV-positive subjects.

Keywords

HIV-infectionemotional deficitanhedoniadepressionpsychopathology
Type
Original article
Information
European Psychiatry , Volume 10 , Issue 7 , 1995 , pp. 345 - 351
Copyright
Copyright © Elsevier, Paris 1995

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References

Abrams, RTaylor, MA.A rating scale for emotional blunting. Am J Psychiatry 1978; 135: 226–9Google ScholarPubMed
Alpert, MRush, MComparison of affects in Parkinson's disease and schizophrenia. Psychopharmacol Bull 1987; 19: 119–20Google Scholar
American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders. 3rd Ed Revised (DSM-III-R).Washington DC: American Psychiatric Association, 1987Google Scholar
Angrist, BD'Hollosy, MSanfilipo, M et al. Central nervous system stimulants as symptomatic treatment for AIDS related neuropsychiatrie impairment. J Clin Psychopharmacol 1992; 12: 268–72CrossRefGoogle Scholar
Berger, JRKumar, MKumar, AFemandez, JBLevin, BCerebrospinal fluid dopamine in HIV-1 infection. AIDS 1994; 8: 67–71CrossRefGoogle ScholarPubMed
Bungener, CKosmadakis, CJouvent, RWidlöcher, DEmotional and psychopathological disturbances in HIV-infection. Progr Neuro-Psychopharmacol Biol Psychiatry 1993; 17: 927–37CrossRefGoogle ScholarPubMed
Bungener, CLacour, CCarton, SLefrère, JJJouvent, RWidlöcher, DEmotional blunting and sensation seeking in HIV-infected individuals. Eur Psychiatry 1991; 6: 99–102CrossRefGoogle Scholar
Catalan, JPsychiatric manifestations of HIV disease. Baillière's Clinical Gastroenterology 1990; 4: 547–62CrossRefGoogle ScholarPubMed
Center of Disease Control. Revision of the CDC surveillance definition for acquired immunodeficiency syndrome. MMWR 1987 36 (Suppl S1): 3S-15SGoogle Scholar
Fell, MNewman, SHems, M et al. Mood and psychiatric disturbances in HIV and AIDS: change over time. Br J Psychiatry 1993; 162: 604–10CrossRefGoogle Scholar
Fernandez, FAdams, FLevy, JKCognitive impairment due to AIDS-related complex and its response to psychostimulants. Psychosomatics 1988; 29: 38–46CrossRefGoogle ScholarPubMed
Femandez, FAnxiety and the neuropsychiatry of AIDS. J Clin Psychiatry 1989; 50: 11 (suppl): 9–14Google Scholar
Fernandez, FLevy, JPsychiatric Diagnosis and Pharmacotherapy of Patients With HIV-infection, AIDS and HIV-infection. In: Tasman, AGoldfinger, SKaufmann, C, eds. Review Psychiat vol 9. Section V. American Psychiatry Press 1991; 614–30Google Scholar
Gala, CPergami, ACatalan, J et al. The psychosocial impact of HIV-infection in gay men, drug users and heterosexuals. Br J Psychiatry 1993; 163: 651–9CrossRefGoogle ScholarPubMed
Holmes, VFernandez, FLevy, JK.Psychostimulants response in AIDS-related complex patients. J Clin Psychiatry 1989; 50: 5–8Google Scholar
Jouvent, RPartiot, AAmmar, SPierson, ARenault, BWidlöcher, DThe dichotomy of anxious agitated/impulsive versus retarded/blunted depression: a new paradigm for biological and pharmaco-clinical research. The uses of fluoxetine in clinical practice. In: Freeman, HL, ed.Royal Society of Medicine Services International Congress and Symposium Series 1991; 183: 35–44Google Scholar
Jouvent, RVindreau, CMontreuil, MBungener, CWidlöcher, DLa clinique polydimensionnelle de l'humeur dépressive1 Nouvelle version de l'échelle EHD. Psychiatr Psychobiol 1988; 3: 245–53CrossRefGoogle Scholar
Levenson, ALPsychiatrie aspects of AIDS. Psychiatrie Hosp 1988; 3: 109–13Google Scholar
Lipman, RSCovi, LDowning, RWPharmacotherapy of anxiety and depression: rationale and study design. Psychopharmacol Bull 1981; 17: 91–5Google Scholar
Lisoprawsky, AJouvent, RAgonistes dopaminergiques et émoussement affectif L'Encéphale 1988; 15: 197–200Google Scholar
Maj, MPsychiatrie aspects of HIV-1 infection and AIDS. Psychol Med 1990; 20: 547–63CrossRefGoogle Scholar
Mc Allister, RHHerns, MVHarrison, MJ et al. Neurological and neuropsychological performance in HIV seropositive men without symptoms. J Neurol Neurosurg Psychiatry 1992; 55: 143–8CrossRefGoogle Scholar
Montgomery, SAAsberg, MAA new depression scale designed to be sensitive to change. Br J Psychiatry 1979; 134: 382–9CrossRefGoogle ScholarPubMed
Naber, DPerro, CSchick, U et al. Psychiatrie Symptoms and Neuropsychological Deficits in HIV-infection. In: Bunney, et al, eds. Neuropharmacology Berlin, Heidelberg: Springer Verlag, 1990 745–55Google Scholar
Ostrow, DGModels for Understanding the Psychiatric Consequences of AIDS. In: Bridger, TP et al, eds. Psychological, Neuropsychiatrie and Substance Abuse Aspects of AIDS. New York: Raven Press, 1988 85–94Google Scholar
Ostrow, DGBehavioral Aspects of AIDS. New York, London: Plenum Medical Book Company, 1990; 260CrossRefGoogle Scholar
Perry, SFishman, BJacobsberg, LFrances, A.Relationship over 1 year between lymphocyte subsets and psychosocial variables among adults with HIV-infection by human immunodeficiency virus. Arch Gen Psychiatry 1992; 49: 396–401CrossRefGoogle Scholar
Rabkin, JGWilliams, JBRemien, RHGoetz, RKertzner, RGorman, JMDepression, distress, lymphocyte subsets, and human immunodeficiency virus symptoms on two occasions in HIV-positive homosexual men. Arch Gen Psychiatry 1991; 48: 111–9CrossRefGoogle ScholarPubMed
Stein, MMiller, AHTrestman, RLDepression the immune system health and illness. Findings in search of meaning. Arch Gen Psychiatry 1991; 48: 171–7Google Scholar
Widlöcher, DLe Ralentissement Dépressif. Paris: Presses Universitaires de France, 1983; 95Google Scholar
Wilkie, FEisdorfer, CMorgan, RLoewenstein, DSzapocznick, JCognition in early human immunodeficiency virus infection Arch Neurology 1990; 47: 433–40Google ScholarPubMed
Williams, JBRabkin, JGRemien, RHGorman, JMEhrhardt, AAMultidisciplinary baseline assessment of gay men with and without HIV-infection II: standardized clinical assessment of current and lifetime pathology. Arch Gen Psychiatry 1991; 48: 124–30CrossRefGoogle Scholar
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