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The efficacy of a dose-escalated application of transdermal nicotine plus sulpiride in Tourette’s syndrome

Published online by Cambridge University Press:  16 April 2020

SM Dursun  and
MA Reveley
SM Dursun
Affiliation:
Department of Psychiatry, University of Leicester, Robert Kilpatrick Clinical Sciences Building, Leicester Royal Infirmary, PO Box 65, Leicester, LE2 7LX, UK
MA Reveley
Affiliation:
Department of Psychiatry, University of Leicester, Robert Kilpatrick Clinical Sciences Building, Leicester Royal Infirmary, PO Box 65, Leicester, LE2 7LX, UK
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Summary

The addition of a dose-escalated regimen of transdermal nicotine patches (TNP) improved tics of a non-smoker patient with Tourette's syndrome, whose tics did not respond to sulpiride. This improvement, as assessed by the Yale Global Tic Severity Scale, lasted for up to 8 weeks, but not 16 weeks. An explanation for the efficacy of TNP is presented.

Keywords

Tourette’s syndrometicstreatmenttransdermal nicotine patch
Type
Short communication
Information
European Psychiatry , Volume 11 , Issue 4 , 1996 , pp. 204 - 206
Copyright
Copyright © Elsevier, Paris 1996

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