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Deterioration of parkinsonian symptoms following treatment of dopaminergic hallucinosis with olanzapine

Published online by Cambridge University Press:  16 April 2020

J. Rudolf ,
M. Ghaemi  and
S. Schmülling
J. Rudolf
Affiliation:
Klinik für Neurologie der Universität zu Köln, Joseph-Stelzmann-Str. 9, 50924 Cologne, Germany
M. Ghaemi
Affiliation:
Klinik für Neurologie der Universität zu Köln, Joseph-Stelzmann-Str. 9, 50924 Cologne, Germany
S. Schmülling
Affiliation:
Klinik für Neurologie der Universität zu Köln, Joseph-Stelzmann-Str. 9, 50924 Cologne, Germany
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Summary

The atypical antipsychotic drug olanzapine has been proposed for treatment of dopaminergic psychosis in Parkinson's disease (PD). We report on a 68-year-old patient who developed a severe akinetic-rigid extrapyramidal syndrome, accompanied by additional paranoid symptoms, following olanzapine treatment of optic hallucinosis in PD. Olanzapine may also induce clinically relevant extrapyramidal side effects in PD patients.

Keywords

dopaminergic psychosisidiopathic Parkinson's diseaseolanzaphineorganic delusional disorder
Type
Case report
Information
European Psychiatry , Volume 14 , Issue 6 , October 1999 , pp. 356 - 357
Copyright
Copyright © European Psychiatric Association 1999

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