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Depressive disorders in patients with sleep apnea syndrome

Published online by Cambridge University Press:  19 July 2023

N. Rmadi ,
N. Kammoun ,
N. Kotti ,
R. Masmoudi ,
S. Rekik ,
M. L. Masmoudi ,
K. Jmal Hammami ,
J. Masmoudi ,
S. Kammoun  and
S. Msaed
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N. Rmadi
Affiliation:
Department Of Occupational Medicine, HEDI CHAKER hospital
N. Kammoun
Affiliation:
Tunisian Ocupational Health and Safety Institute
N. Kotti
Affiliation:
Department Of Occupational Medicine, HEDI CHAKER hospital
R. Masmoudi*
Affiliation:
Psychiatry A Department
S. Rekik
Affiliation:
Pneumology department, HEDI CHAKER hospital, SFAX, Tunisia
M. L. Masmoudi
Affiliation:
Department Of Occupational Medicine, HEDI CHAKER hospital
K. Jmal Hammami
Affiliation:
Department Of Occupational Medicine, HEDI CHAKER hospital
J. Masmoudi
Affiliation:
Psychiatry A Department
S. Kammoun
Affiliation:
Pneumology department, HEDI CHAKER hospital, SFAX, Tunisia
S. Msaed
Affiliation:
Pneumology department, HEDI CHAKER hospital, SFAX, Tunisia
M. Hajjaji
Affiliation:
Department Of Occupational Medicine, HEDI CHAKER hospital
*
*Corresponding author.

Abstract

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Introduction

A growing body of literature has documented that obstructive sleep apnea syndrome (OSAS) is associated with an increased risk of depressive disorders.

Objectives

This study aimed to determine whether depression is associated with OSAS.

Methods

This was a descriptive prospective comparative study conducted over two years among patients with OSAS. Excessive daytime sleepiness was assessed by the Epworth Sleepiness Score (SES). The presence and intensity of depressive symptoms were screened using the Patient Health Questionnaire PHQ9. Data were analysed using SPSS software.

Results

A total of 139 patients participated in the survey with an average age of 48.98 ± 9.80 years. According to the SES, the study population was divided into two groups: a group including 70 subjects with normal SES (< 11); and a group including 69 subjects with pathological SES (≥11). The PHQ9 depression score was higher in sleepy subjects with SES ≥ 11 compared to non-sleepless subjects; the difference being very highly significant (PHQ9=11.97 ± 4.99 and 6.54 ± 5.27 respectively; p=0.0000). The frequency of mild to moderate depressive disorders was found to be greater in non-sleepy subjects (94.3% and 78.3% respectively; p=0.007). For moderately severe to severe depression, their frequency was more marked in sleepy subjects (21.7% and 5.7% respectively; p=0.007).

Conclusions

Depressive disorders constitute a major comorbidity in OSAS. Therefore, it is necessary to improve the quality of these patients’ health by the early detection of the symptoms of overlapping OSAS and depression.

Disclosure of Interest

None Declared

Type
Abstract
Information
European Psychiatry , Volume 66 , Special Issue S1: Abstracts of the 31st European Congress of Psychiatry , March 2023 , pp. S604
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2023. Published by Cambridge University Press on behalf of the European Psychiatric Association
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