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Decreasing rates of incident schizophrenia cases in psychiatric service: a review of the literature

Published online by Cambridge University Press:  16 April 2020

P Munk-Jørgensen*
Affiliation:
Institute for Basic Psychiatric Research, Department of Psychiatric Demography, Psychiatric Hospital in Aarhus, DK-8240Risskov, Denmark
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Summary

A review of the literature shows that the admission rates of new cases of schizophrenia vary with a factor of two to five in North American studies as well as in European studies. Furthermore, the tendency has been decreasing for the last 40–50 years in Europe. Eighteen studies specifically analyzing the development over the last 20 years are reviewed. The studies preponderantly show significant decreases most probably due to the reduction of the number of available psychiatric beds alongside the decentralization of psychiatry, and to decreasing virulence of schizophrenia. Alternatively, a diagnostic delay of schizophrenia can hardly explain the decrease.

Type
General review
Copyright
Copyright © Elsevier, Paris 1995

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References

Amara, IBConsistency in the diagnosis of the functional psychoses. Can Psychiatr Assoc J 1978; 23: 329–36CrossRefGoogle Scholar
Babigian, HMEpidemiology. In: Kaplan, HIFreedman, AMSadock, BJ eds. Comprehensive textbook of Psychiatry/III. San Francisco, California: Williams and Wilkins, 1980Google Scholar
Babigian, HMGardner, EAMiles, HCRomano, JDiagnostic consistency and change in a follow-up study of 1215 patients. Am J Psychiatry 1965; 121: 895–901CrossRefGoogle Scholar
Bach Jensen, EIs “Schizophrenia, Schizo-affective type” a useful diagnosis?. Eur Arch Psychiatr Neurol Sci 1984; 234: 285–9CrossRefGoogle Scholar
Bamrah, ISFreeman, HLGoldberg, DPEpidemiology of schizophrenia in Salford, 1974–1984. Changes in an urban community over ten years. Br J Psychiatry 1991; 159: 802–10CrossRefGoogle Scholar
Beiser, MIacono, WGErickson, DTemporal stability in the major mental disorders. In: Robins, LNBarrett, JE eds. The validity of psychiatric diagnosis. Baltimore, London: Raven Press, 1989; 77–97Google Scholar
Boyle, MTrends in schizophrenia. Lancet 1990; 335: 853Google Scholar
Castle, DJSome current controversies in the epidemiology of schizophrenia. Current Medical LiteraturePsychiatry The royal Society of Medicine 1993; 4: 3–7Google Scholar
Castle, DWessely, SDer, GMurray, RMThe incidence of operationally defined schizophrenia in Camberwell, 1965–1984. Br J Psychiatry 1991; 159: 790–4CrossRefGoogle Scholar
Cooper, JEDiagnostic change in a longitudinal study of psychiatric patients. Br J Psychiatry 1967; 113: 129–42CrossRefGoogle Scholar
Crow, TJTrends in schizophrenia. Letters to the Editor. Lancet 1990; 335: 851CrossRefGoogle Scholar
Dahl, AABruk av pasientregistre i psykiatrisk forskning i Norge. Muligheder, begrensninger og etiske problemer. Nord Psykiatr Tidsskr 1988; 42: 257–64CrossRefGoogle Scholar
Der, GGupta, SMurray, RMIs schizophrenia disappearing?. Lancet 1990; 335: 513–6CrossRefGoogle Scholar
de Alarcon, JSeagroatt, VGoldacre, MTrends in schizophrenia. Lancet 1990; 335: 852–3Google Scholar
de Alarcon, JSeagroatt, VSellar, CGoldacre, MPopulation-based trends in treatment rates in psychiatry in Oxfordshire 1975–1986. J Public Health Med 1993; 15: 93–102CrossRefGoogle ScholarPubMed
Dickson, WEKnedell, REDoes maintenance lithium therapy prevent recurrences of mania under ordinary clinical conditions?. Psychol Med 1986; 16: 521–30CrossRefGoogle ScholarPubMed
Eagles, JMDecreasing rates of diagnoses of schizophrenia in Denmark. Acta Psychiatr Scand (letter to the editor) 1987; 76: 333–6CrossRefGoogle ScholarPubMed
Eagles, JMIs schizophrenia disappearing?. Br J Psychiatry 1991; 158: 834–5CrossRefGoogle Scholar
Eagles, JMIncidence and epidemiology of schizophrenia in Denmark. Br J Psychiatry (letter to the editor) 1993; 162: 268–9CrossRefGoogle ScholarPubMed
Eagles, JMHunter, DMcCance, CDecline in the diagnosis of schizophrenia among first contacts with psychiatric services in north east Scotland, 1969–1984. Br J Psychiatry 1988; 152: 793–8CrossRefGoogle Scholar
Eagles, JMWhalley, LJDecline in the diagnosis of schizophrenia among first admissions to Scottish mental hospitals from 1969–1978. Br J Psychiatry 1985; 146: 151–4CrossRefGoogle Scholar
Eaton, WWEpidemiology of schizophrenia. Epidemiol Rev 1985; 7: 105–26CrossRefGoogle ScholarPubMed
Eaton, WWUpdate on the epidemiology of schizophrenia. Epidemiol Rev 1991; 13: 320–8CrossRefGoogle ScholarPubMed
Folnegovic, ZFolnegovic-Smalc, VKulcar, ZThe incidence of schizophrenia in Croatia. Br J Psychiatry 1990; 156: 363–5CrossRefGoogle ScholarPubMed
Garvey, MJTuason, VBMania misdiagnosed as schizophrenia. J Clin Psychiatry 1980; 41: 75–8Google ScholarPubMed
Goldhamer, HMarshall, AWPsychosis and civilization. Two studies in the frequency of mental disease Glencoe Illinois: The Free Press 1949CrossRefGoogle Scholar
Graham, PMTrends in schizophrenia. Lancet 1990; 335: 852Google Scholar
Gupta, RMMurray, RMThe changing incidence of schizophrenia: Fact or Artifact?. Directions in Psychiatry 1991; 11: 2–7Google Scholar
Hailey, AMHurry, LJPowell, MPsychiatric services in Camberwell and Salford: statistics from the Camberwell and Salford register: 1964–1973. Glencoe, Illinois: MRC Social Psychiatric Unit, 1974Google Scholar
Hare, EWas insanity on the increase?. (lecture) Br J Psychiatry 1983; 142: 439–55CrossRefGoogle ScholarPubMed
Hare, ESchizophrenia as a recent disease. Br J Psychiatry 1988; 153: 521–31CrossRefGoogle ScholarPubMed
Harrison, GCooper, JEWhy isn't schizophrenia disappearing in Nottingham?. Schizophr Res 1991; 4: 259CrossRefGoogle Scholar
Harrison, GCooper, JEGancarczyk, RChanges in the administrative incidence of schizophrenia. Br J Psychiatry 1991; 159: 811–6CrossRefGoogle ScholarPubMed
Hollingshead, ABRedlich, FCSocial class and mental illness: a community study. London: Wiley, 1958CrossRefGoogle Scholar
Horgan, DChange of diagnosis to manic-depressive illness. Psychol Med 1981; 11: 517–23CrossRefGoogle Scholar
Hafner, HEpidemiology of schizophrenia. In: Häfner, HGattaz, WFJanzarik, W eds. Search for the causes of schizophrenia. New York: Springer-Verlag, 1987CrossRefGoogle Scholar
Häfner, Han der Heiden, WThe contribution of European case registers to research on schizophrenia. Schizophr Bull 1986; 12: 26–51CrossRefGoogle ScholarPubMed
Häfner, HGattaz, WFLetter to the Editor. Eur Arch Psychiatry Clin Neurosci 1991; 240: 374–6Google Scholar
Häfner, HReimann, HSpatial distribution of mental disorders in Mannheim 1965. In: Hare, EGWing, JK eds. Psychiatric epidemiology — Proceedings of the International Symposium Aberdeen University, July 22–25 Berlin, Heidelberg: Oxford University Press, 1970Google Scholar
Jablensky, ASartorius, NErnberg, G, et al. Schizophrenia: manifestations, incidence and course in different cultures. A World Health Organization Ten-Country Study Psychol Med Monograph 1992 (suppl 20)CrossRefGoogle Scholar
Joyce, PRChanging trends in first admissions and readmissions for mania and schizophrenia in New Zealand 1974 to 1984. Aust N Z J Psychiatry 1987; 21: 82–6CrossRefGoogle ScholarPubMed
Jørgensen, PLong-term course of acute reactive paranoid psychosis. A follow-up study. Acta Psychiatr Scand 1985; 71: 30–7CrossRefGoogle ScholarPubMed
Jørgensen, PMortensen, PBAdmission pattern and diagnostic stability of patients with functional psychoses in Denmark during a two-year observation period. Acta Psychiatr Scand 1988; 78: 361–5CrossRefGoogle ScholarPubMed
Kaelbling, RVolpe, PAConstancy of psychiatric diagnoses in re-admissions. Compr Psychiatry 1963; 4: 29–39CrossRefGoogle Scholar
Kendell, REThe stability of psychiatric diagnoses. Br J Psychiatry 1974; 124: 352–6CrossRefGoogle Scholar
Kendell, REThe role of diagnosis in psychiatry. Oxford, London: Blackwell Scientific Publications, 1975Google Scholar
Kendell, REMalcolm, DEAdams, WIs the incidence of schizophrenia falling?. Schizophr Res 1992; 6: 100–1CrossRefGoogle Scholar
Kendell, REMalcolm, DEAdams, WThe problem of detecting changes in the incidence of schizophrenia. Br J Psychiatry 1993; 162: 212–8CrossRefGoogle ScholarPubMed
Kierulff, SRasmussen, SBrockhattingen, ADiagnostisk mobilitet i psykiatrien. Ugeskr L˦g 1991; 153: 3384–5Google Scholar
Kramer, MApplications of mental health statistics. Oxford, London: World Health Organization, 1969Google Scholar
Lewis, SFalling incidence of schizophrenia?. Br J Psychiatry 1985; 146: 560–1CrossRefGoogle Scholar
Malzberg, BThe frequency of mental disease. A study of trends in New York State. Acta Psychiatr Scand 1963; 39: 19–30CrossRefGoogle ScholarPubMed
Manderscheid, RWLocke, BZPato, CNShore, DTrends in schizophrenia. Lancet 1990; 335: 1097–8CrossRefGoogle Scholar
Mortensen, PBMunk-Jørgensen, PStrömgren, ELetter to the editor. Eur Arch Psychiatry Clin Neurosci 1991; 240: 374Google Scholar
Munk-Jørgensen, PThe schizophrenia diagnosis in Denmark. A register based investigation. Acta Psychiatr Scand 1985; 72: 266–73CrossRefGoogle Scholar
Munk-Jørgensen, PDecreasing first-admission rates of schizophrenia among males in Denmark from 1970 to 1984. Changing diagnostic patterns?. Acta Psychiatr Scand 1986; 73: 645–50CrossRefGoogle ScholarPubMed
Munk-Jørgensen, PWhy has the incidence of schizophrenia in Danish psychiatric institutions decreased since 1970?. Acta Psychiatr Scand 1987a; 75: 62–8CrossRefGoogle ScholarPubMed
Munk-Jørgensen, PDecreasing rates of diagnoses of schizophrenia in Denmark — In reply. Acta Psychiatr Scand 1987b; 76: 334–5Google Scholar
Munk-Jørgensen, PAre incidence rates of schizophrenia decreasing?. Epidemiologia e Psychiatria Sociale 1993; 2: 7–9CrossRefGoogle Scholar
Munk-Jørgensen, PJorgensen, PDecreasing rates of first-admission diagnoses of schizophrenia among females in Denmark 1970–1984. Acta Psychiatr Scand 1986; 74: 379–83CrossRefGoogle Scholar
Munk-Jørgensen, PKastrup, MMortensen, PBThe Danish psychiatric register as a tool in epidemiology. Acta Psychiatr Scand 1993; 370 (suppl): 27–32CrossRefGoogle ScholarPubMed
Munk-Jørgensen, PMortensen, PBSchizophrenia: a 13-year follow-up. Diagnostic and psychopathological aspects. Acta Psychiatr Scand 1989; 79: 391–9CrossRefGoogle ScholarPubMed
Munk-Jørgensen, PMortensen, PBIncidence and other aspects of the epidemiology of schizophrenia in Denmark, 1971–1987. Br J Psychiatry 1992; 161: 489–95CrossRefGoogle Scholar
Munk-Jørgensen, PMortensen, PBIs schizophrenia really on the decrease?. Eur Arch Psychiatry Clin Neurosci 1993; 242: 244–7CrossRefGoogle ScholarPubMed
Munk-Jørgensen, PMortensen, PBIncidence and epidemiology of schizophrenia in Denmark. Br J Psychiatry 1993b; 162: 268–9Google Scholar
Murray, RMGupta, SDer, GTrends in schizophrenia. Letters to the Editor. Lancet 1990; 335: 1214CrossRefGoogle Scholar
Murray, RMGupta, SDer, GReply: The incidence of schizophrenia, and of causal environmental factors, varies in time and place. Eur Arch Psychiatry Clin Neurosci 1991; 240: 477–8Google Scholar
Niskanen, PAchté, KA The course and prognosis of schizophrenic psychoses in Helsinki. A comparative study of first admissions in 1950, 1960 and 1965 Monographs from the Psychiatric Clinic of the Helsinki University Central Hospital No. 4 1972Google Scholar
Nuallain, MNO'Hare, AWalsh, DIncidence of schizophrenia in Ireland. Psychol Med 1987; 17: 943–8CrossRefGoogle Scholar
Parker, GO'Donnell, MWalter, SChanges in the diagnoses of the functional psychoses associated with the introduction of lithium. Br J Psychiatry 1985; 146: 377–82CrossRefGoogle ScholarPubMed
Prince, MJPhelan, MCTrends in schizophrenia. Letters to the Editor. Lancet 1990; 335: 851–2Google Scholar
Retterstöl, NParanoid psychoses. The stability of nosological categories illustrated by a personal follow-up investigation. Br J Psychiatry 1968; 114: 553–62CrossRefGoogle ScholarPubMed
Rice, JPRochberg, NEndicott, JLavori, PWMiller, CStability of psychiatric diagnoses. An application to the affective disorders. Arch Gen Psychiatry 1992; 49: 824–30CrossRefGoogle ScholarPubMed
Sartorius, NJablensky, AKorten, A, et al.Early manifestations and first-contact incidence of schizophrenia in different cultures. Preliminary communication Psychol Med 1986; 16 909–28CrossRefGoogle Scholar
Shepherd, MA study of the major psychoses in an English countyMaudsley Monographs, No. 3. Geneva: Chapman & Hall, 1957Google Scholar
Strömgren, EBeiträge zur psychiatrischen Erblehre. Auf Grund von Untersuchungen an einer Inselbevölkerung. London: Munksgaard, 1938Google Scholar
Strömgren, EChanges in the incidence of schizophrenia?. Br J Psychiatry 1987; 150: 1–7CrossRefGoogle ScholarPubMed
Syvänne, SIncidence of schizophrenic diseases in Helsinki in 1929–1938 and 1946–1950. Acta Psychiatr Scand 1952; 80 (suppl): 53–9Google ScholarPubMed
Terris, MUse of hospital admissions in epidemiologic studies of mental disease. Arch Gen Psychiatry 1965; 12: 420–6CrossRefGoogle ScholarPubMed
Waddington, JLYoussef, HA The declining incidence of schizophrenia in a rural Irish population of unusual homogeneity: Secular trend towards early onset and male preponderance Schizophrenia Research 6 Abstracts of the VIth Biennial European Workshop of schizophrenia 1992; 101CrossRefGoogle Scholar
Waddington, JLYoussef, HAEvidence for a gender-specific decline in rate of schizophrenia in rural Ireland over a 50-year period. Br J Psychiatry 1994; 164: 171–6CrossRefGoogle Scholar
Warner, Rde Girolamo, GEpidemiology of schizophreniaSeries on Epidemiology of mental disorders and psychosocial problems vol 3 World Health Organization, Geneva: (in press), 1994Google Scholar
Warthen, FJKlee, GDBahn, AK, et al.Diagnosed schizophrenia in MarylandPsychiatric Research Report 22. American Psychiatric Association, 1967Google Scholar
Watts, CAHA long-term follow-up of schizophrenic patients: 1946–1983. J Clin Psychiatry 1985; 46: 210–6Google ScholarPubMed
Weeke, AAdmission pattern and diagnostic stability among unipolar and bipolar manic-depressive patients. Acta Psychiatr Scand 1984; 70: 603–13CrossRefGoogle ScholarPubMed
Wing, JKCooper, JESartorius, NMeasurement and classification of psychiatric symptoms. An instruction manual for the PSE and Catego Program Cambridge University Press 1974Google Scholar
Wing, JKFryers, TStatistics from the Camberwell and Salford psychiatric registers 1964–1974. Cambridge: Institute of Psychiatry, 1976Google Scholar
Wulff, HRRationel klinik. Grundlaget for diagnostiske og terapeutiske beslutninger. Munksgaard, København, 1973Google Scholar
Ødegaard, OAn official diagnostic classification in actual hospital practice. Acta Psychiatr Scand 1966; 42: 329–37CrossRefGoogle Scholar
Ødegaard, OHospitalized psychoses in Norway: Time trends 1926–1965. Social Psychiatry 1971; 6: 54–8CrossRefGoogle Scholar
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