Hostname: page-component-586b7cd67f-2brh9 Total loading time: 0 Render date: 2024-11-29T14:38:09.091Z Has data issue: false hasContentIssue false
  • English
  • Français

Culturally adapted psychoeducation for bipolar disorder in a low-resource setting: protocol for a multicentre randomized controlled trial

Published online by Cambridge University Press:  19 July 2023

I. Husain ,
M. Umer ,
M. Asif ,
A. Bukhsh ,
T. Kiran ,
M. Ansari ,
H. Aslam ,
M. Bhatia ,
F. Dogar  and
O. Husain
...Show all authors
I. Husain
Affiliation:
Centre for Addiction and Mental Health, Toronto, Canada
M. Umer*
Affiliation:
Centre for Addiction and Mental Health, Toronto, Canada
M. Asif
Affiliation:
Ishrat Husain Pakistan Institute of Living and Learning, Karachi
A. Bukhsh
Affiliation:
Ishrat Husain Pakistan Institute of Living and Learning, Karachi
T. Kiran
Affiliation:
Ishrat Husain Pakistan Institute of Living and Learning, Karachi
M. Ansari
Affiliation:
Liaquat University of Medical and Health Sciences, Hyderabad, Pakistan
H. Aslam
Affiliation:
Allama Iqbal Medical College/Jinnah Hospital, Lahore
M. Bhatia
Affiliation:
Peoples University of Medical and Health Sciences for Women, Nawabshah
F. Dogar
Affiliation:
Punjab Institute of Mental Health, Lahore
O. Husain
Affiliation:
Centre for Addiction and Mental Health, Toronto, Canada
H. A. Khan
Affiliation:
Balochistan Institute of Psychiatry And Behavioral Sciences, Quetta
A. A. Mufti
Affiliation:
Jinnah Medical College, Peshawar
B. Mulsant
Affiliation:
Centre for Addiction and Mental Health, Toronto, Canada
F. Naeem
Affiliation:
Centre for Addiction and Mental Health, Toronto, Canada
H. A. Naqvi
Affiliation:
DOW University of Health Sciences, Karachi
C. De Oliveria
Affiliation:
Centre for Addiction and Mental Health, Toronto, Canada
S. Siddiqui
Affiliation:
National Psychiatric Hospital, Multan
A. Tamizuddin
Affiliation:
Institute of Psychiatry, WHO Collaborating Centre for Mental Health Research and Training, Rawalpindi, Pakistan
W. Wang
Affiliation:
Centre for Addiction and Mental Health, Toronto, Canada
J. Zaheer
Affiliation:
Centre for Addiction and Mental Health, Toronto, Canada
N. Husain
Affiliation:
Division of Psychology and Mental Health, School of Health Sciences, Manchester, United Kingdom
N. Chaudhry
Affiliation:
Ishrat Husain Pakistan Institute of Living and Learning, Karachi
I. Chaudhry
Affiliation:
Ziauddin University, Karachi, Pakistan
*
*Corresponding author.

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Introduction

Bipolar disorder (BD) is a source of marked disability, morbidity, and premature death. There is a paucity of research on personalized psychosocial interventions for BD, especially in lowresource settings. A previously published pilot randomized controlled trial (RCT) of a Culturally adapted PsychoEducation (CaPE) intervention for BD in Pakistan reported higher patient satisfaction, enhanced medication adherence, knowledge and attitudes towards BD, and improvement in mood symptom scores and health-related quality of life measures compared to treatment-as-usual (TAU).

Objectives

This protocol describes a larger multicentre RCT to confirm the clinical and cost-effectiveness of CaPE in Pakistan.

Methods

A multicentre individual, parallel arm, RCT of CaPE in 300Pakistani adults with BD. Participants over the age of 18, with adiagnosis of bipolar I and II and who are currently euthymic, will berecruited from seven sites including Karachi, Lahore, Multan, Rawalpindi,Peshawar, Hyderabad and Quetta. Time to recurrence will be the primaryoutcome assessed using Longitudinal Interval Follow-up Evaluation(LIFE). Secondary measures will include mood symptomatology, qualityof life and functioning, adherence to psychotropic medications, andknowledge and attitudes towards BD.

Results

Full ethics approval has been received from National Bioethics Committee (NBC) of Pakistan and Centre for Addiction and Mental Health (CAMH), Toronto, Canada. The study has completed sixty-five screening across the seven centres, of which forty-eight participants have been randomised.

Conclusions

A successful trial will lead to rapid implementation of CaPE in clinical practice, not only in Pakistan, but also in other low-resource settings including those in high-income countries, to improve clinical outcomes, social and occupational functioning, and quality of life in South Asian and other minority patients with BD.

Disclosure of Interest

None Declared

Type
Abstract
Information
European Psychiatry , Volume 66 , Special Issue S1: Abstracts of the 31st European Congress of Psychiatry , March 2023 , pp. S384
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2023. Published by Cambridge University Press on behalf of the European Psychiatric Association
Submit a response

Comments

No Comments have been published for this article.