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Comorbidity in obsessive-compulsive disorder: focus on depression

Published online by Cambridge University Press:  16 April 2020

A Milanfranchi ,
D Marazziti ,
C Pfanner ,
S Presta ,
P Lensi ,
S Ravagli  and
GB Cassano
A Milanfranchi
Affiliation:
Institute of Psychiatry, University of Pisa, via Roma, 67, I-56100Pisa, Italy
D Marazziti*
Affiliation:
Institute of Psychiatry, University of Pisa, via Roma, 67, I-56100Pisa, Italy
C Pfanner
Affiliation:
Institute of Psychiatry, University of Pisa, via Roma, 67, I-56100Pisa, Italy
S Presta
Affiliation:
Institute of Psychiatry, University of Pisa, via Roma, 67, I-56100Pisa, Italy
P Lensi
Affiliation:
Institute of Psychiatry, University of Pisa, via Roma, 67, I-56100Pisa, Italy
S Ravagli
Affiliation:
Institute of Psychiatry, University of Pisa, via Roma, 67, I-56100Pisa, Italy
GB Cassano
Affiliation:
Institute of Psychiatry, University of Pisa, via Roma, 67, I-56100Pisa, Italy
*
*Correspondence and reprints.
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Summary

The authors investigated the comorbidity between obsessive-compulsive disorder (OCD) and other psychiatric disorders in a group of 154 outpatients. The influence of an associate major depressive disorder (MDD) on the outcome of treatment with clomipramine was examined in a subgroup of 52 patients. The results showed that MDD was the most frequent disorder associated with OCD (almost 20% of the patients), followed by generalized anxiety and panic disorder. The co-presence of depression delayed the effect of clomipramine.

Keywords

obsessive-compulsive disorderdepressioncomorbidityclomipramine
Type
Original article
Information
European Psychiatry , Volume 10 , Issue 8 , 1995 , pp. 379 - 382
Copyright
Copyright © Elsevier, Paris 1995

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