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Childbirth hospitalizations in Bipolar disorder patients: a nationwide study protocol

Published online by Cambridge University Press:  01 September 2022

G. Araújo ,
M. Gonçalves-Pinho ,
A.R. Ferreira ,
L. Fernandes  and
A. Freitas
G. Araújo*
Affiliation:
University of Porto, Faculty Of Medicine, Porto, Portugal
M. Gonçalves-Pinho
Affiliation:
CINTESIS - Center for Health Technology and Services, Faculty of Medicine, University of Porto, Department Of Community Medicine, Information And Health Decisions Sciences, Porto, Portugal Centro Hospitalar do Tâmega e Sousa, Departamento De Psiquiatria E Saúde Mental, Penafiel, Portugal Faculty of Medicine, University of Porto, Department Of Community Medicine, Information And Health Decision Sciences (medcids), Porto, Portugal
A.R. Ferreira
Affiliation:
University of Porto, Faculty Of Medicine, Porto, Portugal CINTESIS - Center for Health Technology and Services, Faculty of Medicine, University of Porto, Department Of Community Medicine, Information And Health Decisions Sciences, Porto, Portugal Faculty of Medicine, University of Porto, Department Of Clinical Neurosciences And Mental Health, Porto, Portugal
L. Fernandes
Affiliation:
CINTESIS - Center for Health Technology and Services, Faculty of Medicine, University of Porto, Department Of Community Medicine, Information And Health Decisions Sciences, Porto, Portugal Faculty of Medicine, University of Porto, Department Of Clinical Neurosciences And Mental Health, Porto, Portugal Psychiatry Service, Centro Hospitalar Universitário De São João, Porto, Portugal
A. Freitas
Affiliation:
CINTESIS - Center for Health Technology and Services, Faculty of Medicine, University of Porto, Department Of Community Medicine, Information And Health Decisions Sciences, Porto, Portugal Faculty of Medicine, University of Porto, Department Of Community Medicine, Information And Health Decision Sciences (medcids), Porto, Portugal
*
*Corresponding author.

Abstract

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Introduction

Bipolar disorder (BD) is usually diagnosed in adulthood, around childbearing age. Research has shown that BD has deleterious effects on pregnant women and birth outcomes. However, few nationwide studies using administrative data have approached this at-risk population focusing specifically on childbirth.

Objectives

This study aims to characterize hospitalizations of women with BD in the peripartum period regarding sociodemographic and clinical variables and to investigate the impact BD has on hospitalization outcomes.

Methods

An observational retrospective study will be performed using an administrative database that comprises routinely collected hospitalization data from all mainland Portuguese public hospitals. International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes will be used to identify all women’s admissions for childbirth purposes (V27.X) and codes 296.XX (except 296.2X, 296.3X, 296.9X) will be used to ascertain BD. Episodes will be assigned to one of two mutually exclusive groups (with vs without BD). Multivariate methods will be used to compare both groups concerning key variables and outcomes. This work will comply with the RECORD statement recommendations.

Results

Descriptive and analytical statistics will be conducted in order to describe and characterize this group of patients. Results will be presented as crude and adjusted odds ratio quantifying the risk associated with BD in pregnancy, childbirth and hospitalization outcomes. Findings will be disseminated via publication in peer-reviewed journals.

Conclusions

With this nationwide analysis, we expect to contribute to a better understanding of the demographic and clinical profile of pregnant women with BD and to encourage timely medical and psychological interventions during gestation and childbirth.

Disclosure

No significant relationships.

Keywords

ChildbirthHospitalizationsPregnancybipolar disorder
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S758
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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