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Association between autoimmune diseases and mental disorders in children and adolescents

Published online by Cambridge University Press:  19 July 2023

Z. Elmaataoui ,
H. Belhadga  and
H. Kisra
Z. Elmaataoui*
Affiliation:
Hospital AR-Razi of Sale, Sale, Morocco
H. Belhadga
Affiliation:
Hospital AR-Razi of Sale, Sale, Morocco
H. Kisra
Affiliation:
Hospital AR-Razi of Sale, Sale, Morocco
*
*Corresponding author.

Abstract

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Introduction

Autoimmune diseases play a role in the etiology of a range of psychotic disorders which has attracted increasing interest in recent decades. This hypothesis is supported by genetic findings linking markers related to the immune system and mental disorders, and by clinical studies revealing increased levels of inflammatory markers in patients with mental disorders

Objectives

The objective of our work is to discuss the involvement of autoimmune diseases in the development of mental disorders in children and adolescents.

Methods

We conducted our study through the analysis of three clinical observations.

Results

These were three patients followed in the child psychiatry department for a characterized depressive disorder, an ASD and an acute psychotic attack, and in whom an autoimmune disease was revealed either in the history or on paraclinical explorations.

Conclusions

It appears legitimate to evoke and search for these autoimmune pathologies among the other organic etiologies, in front of any child or adolescent presenting acute and atypical psychiatric symptoms, tables of cognitive regression and resistances to the usual treatments. Biological immunological examinations, even invasive ones, should be repeated, if necessary.

Disclosure of Interest

None Declared

Type
Abstract
Information
European Psychiatry , Volume 66 , Special Issue S1: Abstracts of the 31st European Congress of Psychiatry , March 2023 , pp. S749
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2023. Published by Cambridge University Press on behalf of the European Psychiatric Association
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