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Assessment of health-related quality of life in asthmatic patients

Published online by Cambridge University Press:  19 July 2023

A. Omrane ,
I. Touil ,
R. Romdhani ,
Y. Brahem ,
S. Bouchareb ,
L. Boussoffara ,
J. Kneni ,
T. Khalfallah  and
N. Keskes
A. Omrane*
Affiliation:
Occupational Medicine and Ergonomics
I. Touil
Affiliation:
Pneumology department, Faculty of Medicine of Monastir Tunisia, Monastir, Tunisia
R. Romdhani
Affiliation:
Occupational Medicine and Ergonomics
Y. Brahem
Affiliation:
Pneumology department, Faculty of Medicine of Monastir Tunisia, Monastir, Tunisia
S. Bouchareb
Affiliation:
Pneumology department, Faculty of Medicine of Monastir Tunisia, Monastir, Tunisia
L. Boussoffara
Affiliation:
Pneumology department, Faculty of Medicine of Monastir Tunisia, Monastir, Tunisia
J. Kneni
Affiliation:
Pneumology department, Faculty of Medicine of Monastir Tunisia, Monastir, Tunisia
T. Khalfallah
Affiliation:
Occupational Medicine and Ergonomics
N. Keskes
Affiliation:
Pneumology department, Faculty of Medicine of Monastir Tunisia, Monastir, Tunisia
*
*Corresponding author.

Abstract

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Introduction

Asthma is a common worldwide, chronic respiratory disease. It has been shown to impair a person’s health-related quality of life (HR-QoL), but the core influencing factors are not fully understood.

Objectives

We aimed in this study to evaluate QoL of asthmatic patients and its main determinants.

Methods

A prospective single center study was held with asthmatics consulting in the Pulmonology Department a public hospital in Tunisia. A complete structured questionnaire concerning socio-demographic and clinical characteristics were determined. The assessment of asthma control during the last 4 weeks was based on the GINA 2022 report criteria. The quality of life was assessed by the Asthma Quality of Life Questionnaire (AQLQ) scale in its validated Arabic version.

Results

A total of 109 asthmatic patients was included. Most of them were female (N= 73, 67%). Twelve (11%) were current or ex-smokers. The majority of patients (N=101, 92.6%) were active. Thirty-nine patients (35.7%) had comordidities. Asthma were controlled in 40.4% of cases.

The average of AQLQ was4.9±1.2. The most affected domains were environmental stimuli and symptoms with a mean value of 4.6 ± 1.3 and 5.0± 1.3 respectively.

Allergic and uncontrolled asthma and severe disease were significantly associated with the average of AQLQ in the study population with p respectively 0.001, <0.000 and <0.000.

Multivariate analysis demonstrated that factors independently associated with the HR-QoL were : the severity of asthma (OR-0.39, IC95% [-0.62,-0.15], p=0.001) and uncontrolled disease (OR=0.59, IC95%,[-0.87,-0.31], p=0.000).

Conclusions

These results suggest that uncontrolled and severe asthma significantly affect health asthma-related quality of life.

Disclosure of Interest

None Declared

Type
Abstract
Information
European Psychiatry , Volume 66 , Special Issue S1: Abstracts of the 31st European Congress of Psychiatry , March 2023 , pp. S895
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2023. Published by Cambridge University Press on behalf of the European Psychiatric Association
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