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Addressing the Comorbidity Between Epilepsy and Psychiatric Disorders

Published online by Cambridge University Press:  27 August 2024

A. H. I. Abu Shehab ,
T. Simona ,
U. Ion ,
D. C. Voinescu ,
C.-F. Buciu  and
A. Ciubară
A. H. I. Abu Shehab*
Affiliation:
1Psychiatry Department, “Elisabeta Doamna” Psychiatric Hospital, Galati
T. Simona
Affiliation:
2Psychiatry Department, Carol Davila University of Medicine and Pharmacy, Bucharest
U. Ion
Affiliation:
3Psychiatry Department, University of Medicine and Pharmacy of Craiova, Craiova
D. C. Voinescu
Affiliation:
4Rheumatology department, “Dunărea de Jos” University - Faculty of Medicine and Pharmacy, Galati
C.-F. Buciu
Affiliation:
5public health and management, University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, Târgu Mureș
A. Ciubară
Affiliation:
6Psychiatry Department, “Dunărea de Jos” University - Faculty of Medicine and Pharmacy, Galati, Romania
*
*Corresponding author.

Abstract

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Introduction

The intricate and multifaceted nature of the link between epilepsy and psychiatric diseases is evident. Patients diagnosed with epilepsy frequently exhibit concurrent psychiatric illnesses, including but not limited to depression, anxiety, psychosis, and attention-deficit disorders. Gaining a comprehensive understanding of the fundamental mechanisms and implementing efficacious ways to effectively address this co-occurring medical condition is crucial in order to achieve the most advantageous results for patients.

Objectives

The objective of this study is to examine the frequency, neurobiological bases, and consequences for treatment of psychiatric comorbidities in patients diagnosed with epilepsy. The study aims to offer a thorough understanding of the subject and promote interdisciplinary collaboration.

Methods

A systematic review of literature was conducted, focusing on clinical studies, neuroimaging findings, and neurochemical changes in patients with both epilepsy and psychiatric disorders. Additionally, best-practice recommendations for the clinical management of this patient population were identified.

Results

The results suggest that the coexistence of epilepsy and psychiatric diseases may be affected by neuroinflammation, abnormalities in neurotransmitters, and shared genetic factors. In addition, the implementation of integrated therapy techniques that include both neurological and psychological components has demonstrated encouraging findings in enhancing patient outcomes.

Conclusions

The identification and proficient management of psychiatric comorbidities in individuals with epilepsy are of utmost significance. The establishment of interdisciplinary collaboration between neurologists and psychiatrists, supported by continuous research, is necessary in order to provide comprehensive treatment and enhance the overall well-being of individuals affected by these conditions.

Disclosure of Interest

None Declared

Type
Abstract
Information
European Psychiatry , Volume 67 , Special Issue S1: Abstracts of the 32nd European Congress of Psychiatry , April 2024 , pp. S474 - S475
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of European Psychiatric Association
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