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Spousal resemblance in psychopathology: A comparison of parents of children with and without psychopathology

Published online by Cambridge University Press:  23 March 2020

LW Wesseldijk ,
GC Dieleman ,
RJL Lindauer ,
M Bartels ,
G Willemsen ,
JJ Hudziak ,
DI Boomsma  and
CM Middeldorp
LW Wesseldijk*
Affiliation:
Department of Biological Psychology, VU University Amsterdam, Van der Boechorststraat 1, 1081BTAmsterdam, The Netherlands EMGO+ Institute for Health and Care Research, VU University Medical Centre, Amsterdam, The Netherlands
GC Dieleman
Affiliation:
Department of Child and Adolescent Psychiatry/Psychology, Erasmus Medical Center Rotterdam/Sophia Children’s Hospital, Wytemaweg 80, 3015CNRotterdam, The Netherlands
RJL Lindauer
Affiliation:
Department of Child and Adolescent Psychiatry, Academic Medical Center, Meibergdreef 5, 1105AZAmsterdam, The Netherlands De Bascule, Academic Center for Child and Adolescent Psychiatry, Amsterdam, The Netherlands
M Bartels
Affiliation:
Department of Biological Psychology, VU University Amsterdam, Van der Boechorststraat 1, 1081BTAmsterdam, The Netherlands EMGO+ Institute for Health and Care Research, VU University Medical Centre, Amsterdam, The Netherlands Neuroscience Campus Amsterdam, Amsterdam, The Netherlands
G Willemsen
Affiliation:
Department of Biological Psychology, VU University Amsterdam, Van der Boechorststraat 1, 1081BTAmsterdam, The Netherlands EMGO+ Institute for Health and Care Research, VU University Medical Centre, Amsterdam, The Netherlands
JJ Hudziak
Affiliation:
Department of Psychiatry and Medicine (Division of Human Genetics), Center for Children, Youth and Families, University of Vermont, B229Given B Burlington, VT05405, USA
DI Boomsma
Affiliation:
Department of Biological Psychology, VU University Amsterdam, Van der Boechorststraat 1, 1081BTAmsterdam, The Netherlands EMGO+ Institute for Health and Care Research, VU University Medical Centre, Amsterdam, The Netherlands Neuroscience Campus Amsterdam, Amsterdam, The Netherlands
CM Middeldorp
Affiliation:
Department of Biological Psychology, VU University Amsterdam, Van der Boechorststraat 1, 1081BTAmsterdam, The Netherlands Neuroscience Campus Amsterdam, Amsterdam, The Netherlands Department of Child and Adolescent Psychiatry, GGZ inGeest/VU University Medical Center, Amsterdam, The Netherlands
*
*Corresponding author. at: VU University Amsterdam, Department of Biological Psychology, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands. E-mail address:[email protected] (L.W. Wesseldijk).
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Abstract

Background

Spouses resemble each other for psychopathology, but data regarding spousal resemblance in externalizing psychopathology, and data regarding spousal resemblance across different syndromes (e.g. anxiety in wives and attention deficit/hyperactivity disorder [ADHD] in husbands) are limited. Moreover, knowledge is lacking regarding spousal resemblance in parents of children with psychiatric disorders. We investigated and compared spousal resemblance within and across internalizing and externalizing symptom domains in parents of children with and without psychopathology.

Methods

Symptoms of depression, anxiety, avoidant personality, ADHD, and antisocial personality were assessed with the Adult Self Report in 728 mothers and 544 fathers of 778 children seen in child and adolescent psychiatric outpatient clinics and in 2075 mothers and 1623 fathers of 2784 children from a population-based sample. Differences in symptom scores and spousal correlations between the samples were tested.

Results

Parents in the clinical sample had higher symptom scores than in the population-based sample. In both samples, correlations within and across internalizing and externalizing domains of psychopathology were significant. Importantly, correlations were significantly higher in the clinical sample (P = 0.03). Correlations, within and across symptoms, ranged from 0.14 to 0.30 in the clinical sample and from 0.05 to 0.23 in the population-based sample.

Conclusions

This large study shows that spousal resemblance is not only present within but also across symptom domains. Especially in the clinical sample, ADHD symptoms in fathers and antisocial personality symptoms in mothers were correlated with a range of psychiatric symptoms in their spouses. Clinicians need to be alert of these multiple affected families.

Keywords

PsychopathologySpousal resemblanceDepressionADHDAntisocial behavior
Type
Original article
Information
European Psychiatry , Volume 34 , April 2016 , pp. 49 - 55
Copyright
Copyright © European Psychiatry 2016

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References

Galbaud du Fort, GBland, RCNewman, SCBoothroyd, LJSpouse similarity for lifetime psychiatric history in the general population. Psychol Med 1998;28(4):789–802.CrossRefGoogle ScholarPubMed
Cobham, VEDadds, MRSpence, SHThe role of parental anxiety in the treatment of childhood anxiety. J Consult Clin Psychol 1998;66(6):893–905.CrossRefGoogle ScholarPubMed
Owens, EBHinshaw, SPKraemer, HCArnold, LEAbikoff, HBCantwell, DPet al.Which treatment for whom for ADHD? Moderators of treatment response in the MTA. J Consult Clin Psychol 2003;71(3):540–552.CrossRefGoogle ScholarPubMed
Kennard, BDHughes, JLStewart, SMMayes, TNightingale-Teresi, JTao, Ret al.Maternal depressive symptoms in pediatric major depressive disorder: relationship to acute treatment outcome. J Am Acad Child Adolesc Psychiatry 2008;47(6):694–699.CrossRefGoogle ScholarPubMed
Pilowsky, DJWickramaratne, PPoh, EHernandez, MBatten, LAFlament, MFet al.Psychopathology and functioning among children of treated depressed fathers and mothers. J Affect Disord 2014;164: 107–111.CrossRefGoogle ScholarPubMed
Dierker, LCMerikangas, KRSzatmari, PInfluence of parental concordance for psychiatric disorders on psychopathology in offspring. J Am Acad Child Adolesc Psychiatry 1999;38(3):280–288.CrossRefGoogle ScholarPubMed
Merikangas, KRAssortative mating for psychiatric disorders and psychological traits. Arch Gen Psychiatry 1982;39(10):1173–1180.CrossRefGoogle ScholarPubMed
Mathews, CAReus, VIAssortative mating in the affective disorders: a systematic review and meta-analysis. Compr Psychiatry 2001;42(4):257–262.CrossRefGoogle ScholarPubMed
Meyler, DStimpson, JPPeek, MKHealth concordance within couples: a systematic review. Soc Sci Med 2007;64(11):2297–2310.CrossRefGoogle ScholarPubMed
Sakai, JTStallings, MCMikulich-Gilbertson, SKCorley, RPYoung, SEHopfer, CJet al.Mate similarity for substance dependence and antisocial personality disorder symptoms among parents of patients and controls. Drug Alcohol Depend 2004;75(2):165–175.CrossRefGoogle ScholarPubMed
Kim-Cohen, JMoffitt, TETaylor, APawlby, SJCaspi, AMaternal depression and children’s antisocial behavior: nature and nurture effects. Arch Gen Psychiatry 2005;62(2):173–181.CrossRefGoogle ScholarPubMed
Rhule-Louie, DMMcMahon, RJProblem behavior and romantic relationships: assortative mating, behavior contagion, and desistance. Clin Child Fam Psychol Rev 2007;10(1):53–100.CrossRefGoogle ScholarPubMed
van Grootheest, DSvan den Berg, SMCath, DCWillemsen, GBoomsma, DIMarital resemblance for obsessive-compulsive, anxious and depressive symptoms in a population-based sample. Psychol Med 2008;38(12):1731–1740.CrossRefGoogle Scholar
Distel, MARebollo-Mesa, IWillemsen, GDerom, CATrull, TJMartin, NGet al.Familial resemblance of borderline personality disorder features: genetic or cultural transmission?. PLoS One 2009;4(4):e5334CrossRefGoogle ScholarPubMed
Distel, MARebollo-Mesa, IAbdellaoui, ADerom, CAWillemsen, GCacioppo, JTet al.Familial resemblance for loneliness. Behav Genet 2010;40(4):480–494.CrossRefGoogle ScholarPubMed
Boomsma, DISaviouk, VHottenga, JJDistel, MAde Moor, MHVink, JMet al.Genetic epidemiology of attention deficit hyperactivity disorder (ADHD index) in adults. PLoS One 2010;5(5):e10621CrossRefGoogle ScholarPubMed
Joutsenniemi, KMoustgaard, HKoskinen, SRipatti, SMartikainen, PPsychiatric comorbidity in couples: a longitudinal study of 202,959 married and cohabiting individuals. Soc Psychiatry Psychiatr Epidemiol 2011;46(7):623–633.CrossRefGoogle ScholarPubMed
Ask, HIdstad, MEngdahl, BTambs, KNon-random mating and convergence over time for mental health, life satisfaction, and personality: the Nord-Trondelag Health Study. Behav Genet 2013;43(2):108–119.CrossRefGoogle ScholarPubMed
Thomsen, AFOlsbjerg, MAndersen, PKKessing, LVCohabitation patterns among patients with severe psychiatric disorders in the entire Danish population. Psychol Med 2013;43(5):1013–1021.CrossRefGoogle ScholarPubMed
Merikangas, KRSpiker, DGAssortative mating among in-patients with primary affective disorder. Psychol Med 1982;12(4):753–764.CrossRefGoogle ScholarPubMed
Maes, HHNeale, MCKendler, KSHewitt, JKSilberg, JLFoley, DLet al.Assortative mating for major psychiatric diagnoses in two population-based samples. Psychol Med 1998;28(6):1389–1401.CrossRefGoogle ScholarPubMed
Segenreich, DPaez, MSRegalla, MAFortes, DFaraone, SVSergeant, Jet al.Multilevel analysis of ADHD, anxiety and depression symptoms aggregation in families. Eur Child Adolesc Psychiatry 2015;24(5):525–53610.1007/s00787-014-0604-1 [Epub 2014 Aug 26]CrossRefGoogle ScholarPubMed
Faraone, SVAntshel, KMDiagnosing and treating attention-deficit/hyperactivity disorder in adults. World Psychiatry 2008;7(3):131–136.CrossRefGoogle ScholarPubMed
Reich, TVan Eerdewegh, PRice, JMullaney, JEndicott, JKlerman, GLThe familial transmission of primary major depressive disorder. J Psychiatr Res 1987;21(4):613–624.CrossRefGoogle ScholarPubMed
Achenbach, Rescorla, LManual for the ASEBA adult forms & profiles: for ages 18–59: adult self-report and adult behavior checklist Burlington, VT: ASEBA; 2003[xii, 216 p]Google Scholar
CBS, Inkomen, arbeidsdeelname, opleidingsniveau, vermogen en sociale samenhang naar regio Centraal Bureau voor de Statistiek [CBS]; 2014. http://www.cbs.nl/nl-NL/menu/themas/dossiers/nederland-regionaal/cijfers/incidenteel/maatwerk/2014-arbeid-inkomensbron-vermogen-opleiding-sociale-samenhang-mw.htmGoogle Scholar
Boomsma, DIde Geus, EJVink, JMStubbe, JHDistel, MAHottenga, JJet al.Netherlands Twin Register: from twins to twin families. Twin Res Hum Genet 2006;9(6):849–857.CrossRefGoogle ScholarPubMed
Willemsen, GVink, JMAbdellaoui, Aden Braber, Avan Beek, JHDraisma, HHet al.The Adult Netherlands Twin Register: twenty-five years of survey and biological data collection. Twin Res Hum Genet 2013;16(1):271–281.CrossRefGoogle ScholarPubMed
GGZ Nederland, Factsheet specialistische jeugd-ggz 2013 [Available from: http://www.ggznederland.nl/uploads/assets/Factsheet%20GGZ%20Nederland%20-%20Jeugd-ggz%20juli%202013.pdf]Google Scholar
Achenbach, TMDumenci, LRescorla, LADSM-oriented and empirically based approaches to constructing scales from the same item pools. J Clin Child Adolesc Psychol 2003;32(3):328–340.CrossRefGoogle ScholarPubMed
Achenbach, TMDumenci, LRatings of relations between DSM-IV diagnostic categories and items of the Adult Self-Report (ASR) and Adult Behavior Checklist (ABCL) 2003 [Available from: http://www.aseba.org/research/dsm-adultratings.pdf]Google Scholar
Achenbach, TMKrukowski, RADumenci, LIvanova, MYAssessment of adult psychopathology: meta-analyses and implications of cross-informant correlations. Psychol Bull 2005;131: 361–382.CrossRefGoogle ScholarPubMed
Boker, SNeale, MMaes, HWilde, MSpiegel, MBrick, Tet al.OpenMx: an open source extended structural equation modeling framework. Psychometrika 2011;76(2):306–317.CrossRefGoogle ScholarPubMed
Enders, CKBandalos, DLThe relative performance of full information maximum likelihood estimation for missing data in structural equation models. Struct Equ Modeling 2001;8(3):430–457.CrossRefGoogle Scholar
Last, CGHersen, MKazdin, AEFrancis, GGrubb, HJPsychiatric illness in the mothers of anxious children. Am J Psychiatry 1987;144(12):1580–1583.Google ScholarPubMed
Brown, RTBorden, KAClingerman, SRJenkins, PDepression in attention deficit-disordered and normal children and their parents. Child Psychiatry Hum Dev 1988;18(3):119–132.CrossRefGoogle ScholarPubMed
Lahey, BBPiacentini, JCMcBurnett, KStone, PHartdagen, SHynd, GPsychopathology in the parents of children with conduct disorder and hyperactivity. J Am Acad Child Adolesc Psychiatry 1988;27(2):163–170.CrossRefGoogle ScholarPubMed
Barkley, RAAnastopoulos, ADGuevremont, DCFletcher, KEAdolescents with attention deficit hyperactivity disorder: mother-adolescent interactions, family beliefs and conflicts, and maternal psychopathology. J Abnorm Child Psychol 1992;20(3):263–288.CrossRefGoogle ScholarPubMed
Ferro, TVerdeli, HPierre, FWeissman, MMScreening for depression in mothers bringing their offspring for evaluation or treatment of depression. Am J Psychiatry 2000;157(3):375–379.CrossRefGoogle ScholarPubMed
Swartz, HAShear, MKWren, FJGreeno, CGSales, ESullivan, BKet al.Depression and anxiety among mothers who bring their children to a pediatric mental health clinic. Psychiatr Serv 2005;56(9):1077–1083.CrossRefGoogle ScholarPubMed
Tan, SRey, JDepression in the young, parental depression and parenting stress. Australas Psychiatry 2005;13(1):76–79.CrossRefGoogle Scholar
Cooper, PJFearn, VWilletts, LSeabrook, HParkinson, MAffective disorder in the parents of a clinic sample of children with anxiety disorders. J Affect Disord 2006;93(1–3):205–212.CrossRefGoogle ScholarPubMed
Rishel, CWGreeno, CGMarcus, SCAnderson, CEffect of maternal mental health problems on child treatment response in community-based services. Psychiatr Serv 2006;57(5):716–719.CrossRefGoogle ScholarPubMed
Vidair, HBReyes, JAShen, SParrilla-Escobar, MAHeleniak, CMHollin, ILet al.Screening parents during child evaluations: exploring parent and child psychopathology in the same clinic. J Am Acad Child Adolesc Psychiatry 2011;50(5):441–450.CrossRefGoogle ScholarPubMed
Byrne, PSFreeman, JM’Comisky, JGGeneral practitioners observed: a study of personality, intellectual factors, and group behaviour. Br J Med Educ 1970;4(3):176–184.CrossRefGoogle ScholarPubMed
Reynolds, CABaker, LAPedersen, NLMultivariate models of mixed assortment: phenotypic assortment and social homogamy for education and fluid ability. Behav Genet 2000;30(6):455–476.CrossRefGoogle ScholarPubMed
Penrose, LSMental illness in husband and wife: a contribution to the study of assortative mating in man. Psychiatr Q 1944;18(1):161–166.CrossRefGoogle Scholar
Phillips, KFulker, DWCarey, GNagoshi, CTDirect marital assortment for cognitive and personality variables. Behav Genet 1988;18(3):347–356.CrossRefGoogle ScholarPubMed
Cronkite, RCMoos, RHThe role of predisposing and moderating factors in the stress-illness relationship. J Health Soc Behav 1984;25(4):372–393.CrossRefGoogle ScholarPubMed
Eagles, JMBeattie, JABlackwood, GWRestall, DBAshcroft, GWThe mental health of elderly couples. I. The effects of a cognitively impaired spouse. Br J Psychiatry 1987;150: 299–303.CrossRefGoogle ScholarPubMed
van Steijn, DJOerlemans, AMde Ruiter, SWvan Aken, MABuitelaar, JKRommelse, NNAre parental autism spectrum disorder and/or attention-deficit/Hyperactivity disorder symptoms related to parenting styles in families with ASD (+ADHD) affected children?. Eur Child Adolesc Psychiatry 2013;22(11):671–681.CrossRefGoogle ScholarPubMed
Dean, KStevens, HMortensen, PBMurray, RMWalsh, EPedersen, CBFull spectrum of psychiatric outcomes among offspring with parental history of mental disorder. Arch Gen Psychiatry 2010;67(8):822–829.CrossRefGoogle ScholarPubMed
Middeldorp, CMWesseldijk, LWHudziak, JJVerhulst, FCLindauer, RJDieleman, GCParents of children with psychopathology: psychiatric problems and the association with their child’s problems. Eur Child Adolesc Psychiatry 201610.1007/s00787-015-0813-2 [Epub ahead of print]CrossRefGoogle ScholarPubMed
McLanahan, SSandefur, GDGrowing up with a single parent: what hurts, what helps Cambridge, Mass: Harvard University Press; 1994 [viii, 196 p]Google Scholar
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