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The relationship of personality traits to substance abuse in patients with bipolar disorder

Published online by Cambridge University Press:  16 April 2020

Gonzalo Haro ,
Joseph R. Calabrese ,
Christina Larsson ,
Edwin R. Shirley ,
Eva Martín ,
Carmen Leal  and
Pedro L. Delgado
Gonzalo Haro*
Affiliation:
Dual Pathology Unit, Psychiatry Department, Hospital de la Ribera, C/Onda, s/n e 46600 Alzira, Valencia, Spain IDYCA, CEU-Cardenal Herrera University, Moncada, Spain
Joseph R. Calabrese
Affiliation:
University Hospitals of Cleveland, Case Western Reserve University, 11400 Euclid Ave, Cleveland, OH44106, USA
Christina Larsson
Affiliation:
Clínica del Sistema Nervioso Central, 111 Primado Reig Ave, 2nd Floor, 46020Valencia, Spain
Edwin R. Shirley
Affiliation:
University Hospitals of Cleveland, Case Western Reserve University, 11400 Euclid Ave, Cleveland, OH44106, USA
Eva Martín
Affiliation:
Department of Psychiatry, Hospital Clínico Universitario of Valencia, 16 Blasco Iba~nez Ave, 46010Valencia, Spain
Carmen Leal
Affiliation:
Department of Psychiatry, Faculty of Medicine, University of Valencia, 17 Blasco Iba~nez Ave, 46010Valencia, Spain
Pedro L. Delgado
Affiliation:
Department of Psychiatry, The University of Texas Health Sciences Center, San Antonio, TX78229-3900, USA
*
*Corresponding author. Dual Pathology Unit, Psychiatry Department, Hospital de la Ribera, C/Onda, s/n – 46600 Alzira, Valencia, Spain. Tel.: +34 636 99 35 09. E-mail address: [email protected] (G. Haro).
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Abstract

Purpose

The aim of this study is to determine if personality traits contribute to the likelihood of substance abuse in Bipolar Disorder (BD).

Subjects/materials and methods

Fifty-nine patients meeting DSM-IV criteria for BD: 20 without any history of Substance Related Disorder (SRD), 21 with a lifetime history of SRD but without current SRD, and 18 with current SRD. Patients filled out the TCI, the differences were analyzed by ANOVA and the likelihood was obtained by Multinomial Logistic Regression.

Results

Only Novelty Seeking (NS) is statistically different between the groups. Patients with BD with current SRD have higher rates in NS than those with past SRD, and those without a history of SRD. NS was confirmed as a predicting variable, both to current SRD (OR [CI 95%] = 1.039/1.351; p = 0.011) and past SRD (OR [CI 95%] = 1.004/1.277; p = 0.042) on patients with BD.

Discussion

The results shown would appear to confirm the relationship of NS with the SRD, so long as there is no clear evidence that indicates the association of NS with BD.

Conclusions

There appears a greater predisposition to develop SRD in those patients with a higher degree of NS. The use of the Cloninger's TCI could be used in BD to determine the risk of developing an SRD. Early detection might help improve prognosis.

Keywords

Bipolar disorderSubstance related disordersPersonalityCloninger's TCINovelty seeking
Type
Original article
Information
European Psychiatry , Volume 22 , Issue 5 , July 2007 , pp. 305 - 308
Copyright
Copyright © Elsevier Masson SAS 2007

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Footnotes

1

Tel.: +1 216 844 2875.

2

Tel.: +34 96 369 92 96.

3

Tel.: +34 96 386 26 00.

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