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Functional hemisphere imbalance in patients with paranoid or disorganized schizophrenia

Published online by Cambridge University Press:  16 April 2020

B Spivak ,
N Karny ,
G Katz ,
M Radwan ,
A Apter ,
R Master  and
A Weizman
B Spivak
Affiliation:
Research Unit, Ness Ziona Mental Health Center, Ness Ziona and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv
N Karny
Affiliation:
Research Unit, Ness Ziona Mental Health Center, Ness Ziona and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv
G Katz
Affiliation:
Eytanim Psychiatric Hospital, Jerusalem
M Radwan
Affiliation:
Research Unit, Geha Psychiatric Hospital, Beilinson Medical Center, Petah Tiqva
A Apter
Affiliation:
Research Unit, Geha Psychiatric Hospital, Beilinson Medical Center, Petah Tiqva
R Master
Affiliation:
Research Unit, Ness Ziona Mental Health Center, Ness Ziona and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv
A Weizman*
Affiliation:
Research Unit, Geha Psychiatric Hospital, Beilinson Medical Center, Petah Tiqva Geha Psychiatric Hospital and Felsenstein Medical Research Center, Beilinson Medical Center, Petah Tiqva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
*
*Correspondence and reprints: A Weizman, Laboratory of Biological Psychiatry, Felsenstein Medical Research Center, c/o Beilinson Medical Center, Petah Tiqva 49100, Israel.
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Summary

We assessed hemisphere function in right-handed male chronic schizophrenic patients using dichotic listening tests. We evaluated digit, tonic and transitional tests in patients with paranoid schizophrenia (n = 8), patients with disorganized schizophrenia (n = 8) and in control subjects (n = 8). The dichotic listening analysis discriminated between paranoid and disorganized schizophrenia. In disorganized schizophrenia, functional impairment of both hemispheres was demonstrated, while in paranoid schizophrenia dysfunction was more prominent in the right hemisphere. These results indicate the possible involvement of right hemisphere dysfunction in the pathophysiology of chronic paranoid schizophrenia, in contrast to dysfunction of both hemispheres in chronic disorganized schizophrenia.

Keywords

dichotic listeningschizophrenic patientshemispheric function
Type
Original article
Information
European Psychiatry , Volume 11 , Issue 4 , 1996 , pp. 175 - 179
Copyright
Copyright © Elsevier, Paris 1996

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References

Bruder, GECerebral laterality and psychopathology: a review of dichotic listening studies Schizophr Bull 9 1983 34–151CrossRefGoogle ScholarPubMed
Coren, S, Porac, C, Duncan, PA behaviorally validated self-report inventory to assess four types of lateral preference J Clin Neuropsychol 1 1979 55–64CrossRefGoogle Scholar
Cutting, JThe role of right hemisphere dysfunction in psychiatric disorders Br J Psychiatry 160 1992 583–588CrossRefGoogle ScholarPubMed
Flor-Henry, PPsychosis and temporal lobe epilepsy: a controlled investigation Epilepsia 10 1969 363–395CrossRefGoogle ScholarPubMed
Flor-Henry, PLaterality, shifts of cerebral dominance and psychosisGruzelier, J,Flor-Henry, PHemispheric asymmetries of function in psychopathology 1979 Elsevier AmsterdamGoogle Scholar
Gruzelier, JHHemispheric imbalances masquerading as paranoid and non-paranoid syndromes? Schizophr Bull 7 1981 662–673CrossRefGoogle Scholar
Gruzelier, JHA critical assessment and integration of lateral asymmetries in schizophreniaMyslobodsky, MHemisyndromes 1983 Academic LondonGoogle Scholar
Karny, N, Nachshon, IAbnormal lateralization in schizophrenia: empirical evidence for an integrated model Eur Psychiatry 10 1995 75–84CrossRefGoogle ScholarPubMed
Kendler, KS, Davis, KLThe genetics and biochemistry of paranoid schizophrenic and other paranoid psychosis Schizophr Bull 7 1981 689–70910.1093/schbul/7.4.689CrossRefGoogle Scholar
Magaro, PAThe paranoid and the schizophrenic: the case for distinct cognitive style Schizophr Bull 7 1981 632–662CrossRefGoogle ScholarPubMed
Merrin, ELClinical characterization of schizophrenic patients and cerebral asymmetry: review and hypotheses Compr Psychiatry 23 1982 55–67CrossRefGoogle Scholar
Nachshon, IHemispheric dysfunctioning in schizophrenia J Nerv Ment Dis 168 1980 241–242CrossRefGoogle Scholar
Nachshon, IDichotic listening models of cerebral deficit in schizophreniaHugdahl, KHandbook of Dichotic Listening: Theory, Methods and Research 1987 Wiley Sussex, EnglandGoogle Scholar
Newlin, DB, Carpenter, B, Golden, CJHemispheric asymmetries in schizophrenia Biol Psychiatry 16 1981 561–582Google Scholar
Tsuang, MT, Winokur, GCriteria for subtyping schizophrenia Arch Gen Psychiatry 31 1974 43–47CrossRefGoogle ScholarPubMed
Walker, E, McGuire, MIntra- and inter-hemispheric information processing in schizophrenia Psychol Bull 92 1992 701–72510.1037/0033-2909.92.3.701CrossRefGoogle Scholar
Wexler, BECerebral laterality and psychiatry: a review of the literature Am J Psychiatry 137 1980 279–297Google ScholarPubMed
Wexler, BEAlterations in cerebral laterality during acute psychotic illness. II Br J Psychiatry 149 1986 202–209CrossRefGoogle Scholar
Wexler, BE, Giller, EL, Southwick, SCerebral laterality, symptoms and diagnosis in psychotic patients Biol Psychiatry 29 1991 103–116CrossRefGoogle ScholarPubMed
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