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Forebrain dopamine systems — can they help us to understand psychosis?

Published online by Cambridge University Press:  16 April 2020

Anthony Grace
Anthony Grace*
Affiliation:
Departments of Neuroscience, Psychiatry and Psychology, 458 Crawford Hall, University of Pittsburgh, Pittsburgh, PA15260USA
*
*E-mail address:[email protected] (A. Grace).
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Extract

Under normal circumstances, emotional and affective signals within the brain are tempered by signals from higher brain centres, including the forebrain. These control systems ensure that responses to emotional and affective stimuli are appropriate for the environment within which they are generated. In patients with schizophrenia, these control systems are dysfunctional causing the patients to become oversensitive to such emotional stimuli and leading to the exaggerated reactions that are symptomatic of the disease [7,19].

Type
Research Article
Information
European Psychiatry , Volume 18 , Issue S2: Schizophrenia: Improving the treatment through increased understanding - Mind Matters 4th International Psychiatry Forum , December 2003 , pp. 27s - 31s
Copyright
Copyright © 2003 European Psychiatric Association

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