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Differences in clinical and cognitive variables in seasonal affective disorder compared to depressive-related disorders: Evidence from a population-based study in Finland

Published online by Cambridge University Press:  23 March 2020

I. Morales-Muñoz ,
S. Koskinen  and
T. Partonen
I. Morales-Muñoz*
Affiliation:
Department of Health, National Institute for Health and Welfare (THL), P.O. Box 30, Mannerheimintie 168b, Helsinki, FI-00271, Finland
S. Koskinen
Affiliation:
Department of Health, National Institute for Health and Welfare (THL), P.O. Box 30, Mannerheimintie 168b, Helsinki, FI-00271, Finland
T. Partonen
Affiliation:
Department of Health, National Institute for Health and Welfare (THL), P.O. Box 30, Mannerheimintie 168b, Helsinki, FI-00271, Finland
*
* Corresponding author. E-mail address:[email protected] (I. Morales-Muñoz).
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Abstract

Background:

Seasonal affective disorder (SAD) is a type of depression with seasonal pattern. Although it involves some idiosyncratic symptoms, it can overlap with other depressive disorders such as major depressive disorder (MDD) or dysthymia. We aimed to characterize the differences in specific cognitive and clinical symptoms between SAD and depressive-related disorders.

Methods:

In total, 4554 Finnish subjects from the population-based Health 2011 Survey were interviewed with the Munich version of Composite International Diagnostic Interview (M-CIDI) and filled in the Seasonal Pattern Assessment Questionnaire (SPAQ). From this sample for our analysis, we included those participants who fulfilled the criteria for SAD (n = 171), MDD (n = 153) or dysthymia (n = 84) and their 816 psychologically healthy controls matched by age and gender. In addition to M-CIDI and SPAQ, the Beck Depression Inventory, the General Health Questionnaire, an abbreviated version of the Mini-Mental State Examination, the category verbal fluency test, and the CERAD 10-word list were used.

Results:

Subjects with dysthymia showed major deficits in both clinical and cognitive domains compared to MDD, SAD and healthy controls. Although clinical comorbidity was mild in SAD, these participants showed similar cognitive deficits to dysthymic subjects and greater impairments than MDD.

Conclusions:

SAD subjects show a differential clinical and cognitive profile compared to other depressive-related disorders. Although less severe clinical symptoms are found in these individuals, some cognitive impairment already appears in subjects with SAD recruited from a population-based study.

Keywords

CognitionPsychiatric comorbidityDepressiveMoodSeasonality
Type
Original article
Information
European Psychiatry , Volume 44 , July 2017 , pp. 9 - 16
Copyright
Copyright © European Psychiatric Association 2017

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References

Partonen, TLönnqvist, JSeasonal affective disorder. Lancet 1998; 352(9137): 1369–1374.CrossRefGoogle ScholarPubMed
Rosenthal, NESack, DAGillin, JCLewy, AJGoodwin, FKDavenport, Y, et al.Seasonal affective disorder. A description of the syndrome and preliminary findings with light therapy. Arch Gen Psychiatry 1984; 41(1): 72–80.CrossRefGoogle ScholarPubMed
Melrose, S Seasonal affective disorder: an overview of assessment and treatment approaches. Depress Res Treat 2015;178564.CrossRefGoogle Scholar
American Psychiatric Association Diagnostic and statistical manual of mental disorders, 5th ed., Washington DC: APA; 2013.Google Scholar
Forneris, CANussbaumer, BKaminski-Hartenthaler, AMorgan, LCGaynes, BNSonis, JH, et al.Psychological therapies for preventing seasonal affective disorder. Cochrane Database Syst Rev 2015;11:CD011270.Google Scholar
Pjrek, EBaldinger-Melich, PSpies, MPapageorgiou, KKasper, SWinkler, DEpidemiology and socioeconomic impact of seasonal affective disorder in Austria. Eur Psychiatry 2016; 32: 28–33.CrossRefGoogle ScholarPubMed
Benazzi, FVarious forms of depression. Dialogues Clin Neurosci 2006; 8(2): 151–161.Google Scholar
Brunello, NAkiskal, HBoyer, PGessa, GLHowland, RHLanger, SZ, et al.Dysthymia: clinical picture, extent of overlap with chronic fatigue syndrome, neuropharmacological considerations, and new therapeutic vistas. J Affect Disord 1999; 52(1–3): 275–290.CrossRefGoogle ScholarPubMed
MacQueen, GMMemedovich, KACognitive dysfunction in major depression and bipolar disorder: assessment and treatment options. Psychiatry Clin Neurosci 2016 http://dx.doi.org/10.1111/pcn.12463.Google ScholarPubMed
Ragguett, RMCha, DSKakar, RRosenblat, JDLee, YMcIntyre, RSAssessing and measuring cognitive function in major depressive disorder. Evid Based Ment Health 2016; 19(4): 106–109.CrossRefGoogle ScholarPubMed
Gonda, XPompili, MSerafini, GCarvalho, AFRihmer, ZDome, PThe role of cognitive dysfunction in the symptoms and remission from depression. Ann Gen Psychiatry 2015;14:27.CrossRefGoogle ScholarPubMed
Kennedy, SHCore symptoms of major depressive disorder: relevance to diagnosis and treatment. Dialogues Clin Neurosci 2008; 10(3): 271–277.Google ScholarPubMed
Kent, STMcClure, LACrosson, WLArnett, DKWadley, VGSathiakumar, NEffect of sunlight exposure on cognitive function among depressed and non-depressed participants: a REGARDS cross-sectional study. Environ Health 2009;8:34.CrossRefGoogle ScholarPubMed
Merikanto, ILahti, TCastaneda, AETuulio-Henriksson, AAalto-Setälä, TSuvisaari, J, et al.Influence of seasonal variation in mood and behavior on cognitive test performance among young adults. Nord J Psychiatry 2012; 66: 303–310.CrossRefGoogle ScholarPubMed
Hasselbalch, BJKnorr, UHasselbalch, SGGade, AKessing, LVCognitive deficits in the remitted state of unipolar depressive disorder. Neuropsychology 2012; 26: 642–651.CrossRefGoogle ScholarPubMed
Murrough, JWIacoviello, BNeumeister, ACharney, DSIosifescu, DVCognitive dysfunction in depression: neurocircuitry and new therapeutic strategies. Neurobiol Learn Mem 2011; 96: 553–563.CrossRefGoogle ScholarPubMed
Harris, PAllegri, RFDillon, CSerrano, CMLoñ, LVillar, V, et al.[Cognition in dysthymia]. Vertex 2005; 16(61): 165–169.Google Scholar
Airaksinen, ELarsson, MLundberg, IForsell, YCognitive functions in depressive disorders: evidence from a population-based study. Psychol Med 2004; 34(1): 83–91.CrossRefGoogle ScholarPubMed
Levitt, AJJoffe, RTBrecher, DMacDonald, CAnxiety disorders and anxiety symptoms in a clinic sample of seasonal and non-seasonal depressives. J Affect Disord 1993; 28: 51–56.CrossRefGoogle Scholar
Pendse, BPOjehagen, AEngström, GTräskman-Bendz, LSocial characteristics of seasonal affective disorder patients: comparison with suicide attempters with non-seasonal major depression and other mood disorder patients. Eur Psychiatry 2003; 18(1): 36–39.CrossRefGoogle ScholarPubMed
Melartin, TKRytsälä, HJLeskelä, USLestelä-Mielonen, PSSokero, TPIsometsä, ETCurrent comorbidity of psychiatric disorders among DSM-IV major depressive disorder patients in psychiatric care in the Vantaa Depression Study. J Clin Psychiatry 2002; 63: 126–134.CrossRefGoogle ScholarPubMed
Dunn, VGoodyer, IMLongitudinal investigation into childhood- and adolescence-onset depression: psychiatric outcome in early adulthood. Br J Psychiatry 2006; 188: 216–222.CrossRefGoogle ScholarPubMed
Akiskal, HSDysthymia: clinical and external validity. Acta Psychiatr Scand 1994; 383: 19–23.CrossRefGoogle ScholarPubMed
Lundqvist, AMäki-Opas, THealth 2011 Survey: methods. The National Institute for Health and Welfare (THL). Report 8/2016 Helsinki: National Institute for Health and Welfare; 2016Google Scholar
Magnusson, AValidation of the Seasonal Pattern Assessment Questionnaire (SPAQ). J Affect Disord 1996; 40(3): 121–129.CrossRefGoogle Scholar
Thompson, CStinson, DFernandez, MFine, JIsaacs, GA comparison of normal, bipolar and seasonal affective disorder subjects using the Seasonal Pattern Assessment Questionnaire. J Affect Disord 1988; 14: 257–264.CrossRefGoogle ScholarPubMed
Robins, LNWing, JWittchen, HUHelzer, JEBabor, TFBurke, J, et al.The Composite International Diagnostic Interview. An epidemiologic instrument suitable for use in conjunction with different diagnostic systems and in different cultures. Arch Gen Psychiatry 1988; 45(12): 1069–1077.CrossRefGoogle ScholarPubMed
Lachner, GWittchen, HUPerkonigg, AHolly, ASchuster, PWunderlich, U, et al.Structure, content and reliability of the Munich-Composite International Diagnostic Interview (M-CIDI) substance use sections. Eur Addict Res 1998; 4(1–2): 28–41.CrossRefGoogle ScholarPubMed
Rosenthal, NEBradt, GHWehr, TASeasonal Pattern Assessment Questionnaire (SPAQ) Bethesda: National Institute of Mental Health; 1984Google Scholar
Beck, ATWard, CHMendelson, MMock, JErbaugh, JAn inventory for measuring depression. Arch Gen Psychiatry 1961; 4: 561–571.CrossRefGoogle ScholarPubMed
Goldberg, DHillier, VA scaled version of the General Health Questionnaire. Psychol Med 1979; 9(01): 139–145.CrossRefGoogle ScholarPubMed
Folstein, MFFolstein, SEMcHugh, PR“Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12(3): 189–198.CrossRefGoogle ScholarPubMed
Lezak, MDHowieson, DBBigler, EDTranel, DNeuropsychological assessment, 5th ed., New York: Oxford University Press; 2012.Google Scholar
Welsh, KAButters, NMohs, RCBeekly, DEdland, SFillenbaum, G, et al.The consortium to establish a registry for Alzheimer's disease (CERAD). Part V. A normative study of the neuropsychological battery. Neurology 1994; 44: 609–614.CrossRefGoogle Scholar
Larumbe, R[Detection of early cases of Alzheimer's disease. Application of the CERAD neuropsychological test battery]. Rev Med Univ Navarra 1997; 41: 6–11.Google Scholar
Griffiths, JRavindran, AVMerali, ZAnisman, HDysthymia: a review of pharmacological and behavioral factors. Mol Psychiatry 2000; 5(3): 242–261.CrossRefGoogle ScholarPubMed
Freeman, HHow the concept of dysthymia has developed: a biological perspective. In: Licinio, JBolis, CLGold, P, editors. Dysthymia: from clinical neuroscience to treatment Geneva: World Health Organization; 1997.Google Scholar
Klein, DNKocsis, JHMcCullough, JPHolzer, CEHirschfeld, RMKeller, MBSymptomatology in dysthymic and major depressive disorder. Psychiat Clin North Am 1996; 19: 41–53.CrossRefGoogle ScholarPubMed
Keller, MBKlein, DNHirschfeld, RMADocsis, JHMcCullough, JPMiller, IResults of the DSM-IV mood disorders field trial. Am J Psychiatry 1995; 152: 843–849.Google ScholarPubMed
Weissman, MMLeaf, PJBruce, MLFlorio, LThe epidemiology of dysthymia in five communities: rates, risks, comorbidity and treatment. Am J Psychiatry 1988; 145: 815–819.Google ScholarPubMed
Hammar, AÅrdal, GCognitive functioning in major depression – a summary. Front Hum Neurosci 2009;3:26.CrossRefGoogle Scholar
Lam, RWKennedy, SHMclntyre, RSKhullar, ACognitive dysfunction in major depressive disorder: effects on psychosocial functioning and implications for treatment. Can J Psychiatry 2014; 59(12): 649–654.CrossRefGoogle ScholarPubMed
Sullivan, BPayne, TWAffective disorders and cognitive failures: a comparison of seasonal and nonseasonal depression. Am J Psychiatry 2007; 164(11): 1663–1667.CrossRefGoogle ScholarPubMed
Schwartz, PJTurner, EHGarcia-Borreguero, DSedway, JVetticad, RGWehr, TA, et al.Serotonin hypothesis of winter depression: behavioral and neuroendocrine effects of the 5-HT(1A) receptor partial agonist ipsapirone in patients with seasonal affective disorder and healthy control subjects. Psychiatry Res 1999; 86(1): 9–28.CrossRefGoogle ScholarPubMed
Chellappa, SLGordijn, MCCajochen, CCan light make us bright? Effects of light on cognition and sleep. Prog Brain Res 2011; 190: 119–133.CrossRefGoogle ScholarPubMed
Golden, RNGaynes, BNEkstrom, RDHamer, RMJacobsen, FMSuppes, T, et al.The efficacy of light therapy in the treatment of mood disorders: a review and meta-analysis of the evidence. Am J Psychiatry 2005; 162: 656–662.CrossRefGoogle Scholar
Westrin, ALam, RWSeasonal affective disorder: a clinical update. Ann Clin Psychiatry 2007; 19(4): 239–246.CrossRefGoogle ScholarPubMed
Graw, PGisin, BWirz-Justice, AFollow-up study of seasonal affective disorder in Switzerlan. Psychopathology 1997; 30(4): 208–214.CrossRefGoogle Scholar
Meyer, CMuto, VJaspar, MKussé, CLambot, EChellappa, SL, et al.Seasonality in human cognitive brain responses. Proc Natl Acad Sci U S A 2016; 113(11): 3066–3071.CrossRefGoogle ScholarPubMed
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