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Daily life stress reactivity in remitted versus non-remitted depressed individuals

Published online by Cambridge University Press:  15 April 2020

M. van Winkel ,
N.A. Nicolson ,
M. Wichers ,
W. Viechtbauer ,
I. Myin-Germeys  and
F. Peeters
M. van Winkel*
Affiliation:
Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, PO Box 616, 6200MDMaastricht, The Netherlands GGzE, Institute of Mental Health Care Eindhoven and the Kempen, The Netherlands
N.A. Nicolson
Affiliation:
Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, PO Box 616, 6200MDMaastricht, The Netherlands
M. Wichers
Affiliation:
Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, PO Box 616, 6200MDMaastricht, The Netherlands
W. Viechtbauer
Affiliation:
Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, PO Box 616, 6200MDMaastricht, The Netherlands
I. Myin-Germeys
Affiliation:
Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, PO Box 616, 6200MDMaastricht, The Netherlands
F. Peeters
Affiliation:
Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, PO Box 616, 6200MDMaastricht, The Netherlands
*
*Corresponding author. Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands. Tel.: +0031 433299631. E-mail address:[email protected] (M. van Winkel).
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Abstract

Background:

Little is known about how daily life mood reactivity to minor stressors (stress reactivity) might change following major depressive disorder (MDD) treatment. We investigate whether (i) mood states and appraisals of daily stressors change after treatment; (ii) stress reactivity to event, activity, or social stress differs; (iii) stress reactivity depends on severity of residual depressive symptoms; and (iv) stress reactivity in individuals with remitted or non-remitted depression differ from that of never-depressed individuals.

Methods:

Thirty depressed individuals participated in an experience sampling study before and after a treatment period of 18 months; 39 healthy individuals formed a comparison group. Reactivity of positive affect (PA) and negative affect (NA) to daily stressors were measured.

Results:

More residual symptoms were associated with larger NA responses to stress. Compared to healthy controls, participants with non-remitted MDD showed higher NA-reactivity to all stressors. In contrast, stress reactivity to event and activity stressors was normalized in remitted patients. However, they still showed heightened NA-reactivity to social stress.

Conclusions:

Greater stress reactivity to event and activity stress appears to be state-dependent. The heightened social stress reactivity in remitted patients suggests that sensitivity to social stress may reflect an underlying vulnerability in MDD.

Keywords

Major depressive disorderStress reactivityExperience sampling methodDaily lifeMDD treatment
Type
Original article
Information
European Psychiatry , Volume 30 , Issue 4 , June 2015 , pp. 441 - 447
Copyright
Copyright © Elsevier Masson SAS 2015

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