Hostname: page-component-cd9895bd7-lnqnp Total loading time: 0 Render date: 2024-12-18T12:24:07.386Z Has data issue: false hasContentIssue false

Clinical aspects of suicidal behavior relevant to genetics

Published online by Cambridge University Press:  16 April 2020

A. Apter*
Affiliation:
Schneiders Childrens Medical Center of Israel Sackler School of Medicine, University of Tel Aviv, 14 Kaplan St. Petah, 4202Tikva, Israel
*
*E-mail address: [email protected]
Get access

Abstract

A major hindrance to determining the underlying biology of suicide is the heterogeneity of the phenotype. Not only are there various forms of self-harm and suicidal behaviors but even the finite act of dying by suicide can occur in multiple psychosocial contexts. Of all the different forms of fatal and non-fatal suicidal behaviors, the one that received the most attention is the aggressive impulsive type, which seems to occur in younger people and to cut across nosological entities, although its most classical expression occurs in borderline personality disorder. This focus should not obscure the fact that other forms of suicidal behavior such as those related to demoralization or wounded honor (narcissism) may well have different underlying genetic diatheses.

Type
Original article
Copyright
Copyright © Elsevier Masson SAS 2010

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Apter, A, Bleich, A, King, RA, Kron, S, Fluch, A, Kotler, Met al.Death without warning? A clinical postmortem study of suicide in 43 Israeli adolescent males. Arch Gen Psychiatry 1993;50:138142.CrossRefGoogle Scholar
Apter, A, Gothelf, D, Orbach, L, Weizman, R, Ratzoni, G, Har-Even, Det al.Correlation of suicidal and violent behavior in different diagnostic categories in hospitalized adolescent patients. JAACAP 1995;34:912918.Google ScholarPubMed
Brent, DA, Johnson, B, Bartle, S, Bridge, J, Rather, C, Connolly, MJet al.Personality disorder, tendency to impulsive violence, and suicidal behavior in adolescents. JAACAP 1993;32:6975.Google ScholarPubMed
Brent, DA, Johnson, BA, Perper, J, Connolly, J, Bridge, J, Bartle, Set al.Personality disorder, personality traits, impulsive violence, and completed suicide in adolescents. JAACAP 1994;33:10801086.Google ScholarPubMed
Bruch, HEating Disorders. Obesity, Anorexia Nervosa, and the person within. New York: NY Basic Books; 1973.Google Scholar
Conwell, Y, Duberstein, PR, Cox, C, Herrmann, JH, Forbes, NT, Caine, EDRelationships of age and Axis I diagnosis in victims of completed suicide: A psychological autopsy study. Am J Psychiatry 1996;153:10011008.Google ScholarPubMed
Currier, D, Mann, JJStress, genes and the biology of suicidal behavior. Psychiatr Clin North Am 2008;31:247269.CrossRefGoogle ScholarPubMed
King, R.A, Apter, APsychoanalytic perspectives on adolescent suicide. Psychoanal Study Child 1996;51:491505.CrossRefGoogle ScholarPubMed
Levi, Y, Horesh, N, Fischel, T, Treves, I, Or, E, Apter, AMental pain and its communication in medically serious suicide attempts: An “impossible situation”. J Affect Disord 2008;111:244250.CrossRefGoogle Scholar
Van Praag, HMOver the mainstream: Diagnostic requirements for biological psychiatric research. Psychiatr Res 1997;72:201212.CrossRefGoogle ScholarPubMed
Submit a response

Comments

No Comments have been published for this article.