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Atypical depression: diagnosis and therapeutic issues

Published online by Cambridge University Press:  16 April 2020

JR de la Fuente
JR de la Fuente*
Affiliation:
Universitad Nacional Autonoma de Mexico, Facultad de Medicina, Edificio B, Apdo Postal 70-443, 04510México, DF, Mexico
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Summary

A number of Meso-American artifacts which appear to depict subjects presenting severe depressive episodes have been identified, showing that concern with depressive disorders is not a recent phenomenon. Atypical presentations of depression in modern Mexico are characterized by a high degree of somatization, perhaps to avoid the stigma of “mental disorders”. Other characteristics are mood reactivity, substantial anxiety, phobias and the reversed vegetative manifestations. There is a high comorbidity with panic disorder and with bipolar depression. Nosological terminology is not fully standardized, and commonly encountered diagnoses include “neurasthenia”, “neurotic depression”, “mixed depression”, “resistant depression”, etc. Treatment involves a variety of modalities, including TCAs, MAOIs, and anxiolytics, together with a number of drug combinations; open trials are underway with newer agents such as SAMe, SSRIs and the RIMAs.

Keywords

depressionatypical depressiondiagnosistreatment
Type
Research Article
Information
European Psychiatry , Volume 8 , Issue 5: Worldwide therapeutic strategies in atypical depressive syndromes , 1993 , pp. 235 - 240
Copyright
Copyright © European Psychiatric Association 1993

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References

American Psychiatric Association (1993) Practice guideline for major depressive disorder in adults. Am J Psychiatry 150(suppl)4, 1-26Google Scholar
Berlanga, COrtega, HAOntiveros, Met al (1992) Efficacy of S-adenosyl-L-methionine in speeding the onset of action of imipramine. Psychiatry Res 44, 257–262CrossRefGoogle ScholarPubMed
Berlanga, CCanetti, AChávez, Ede la Fuente, JRet al (1991) Tratamiento farmacológico de las Crisis de Angustia. Reporte comparativo de la eficacia y seguridad del alprazolam y la imipramina en un estudio controlado. Rev Salud Mental (Mex) 14, 1–5Google Scholar
Draper, RJDaly, I (1983) Med J 76, 453CrossRefGoogle Scholar
de la Fuente, JR (1983) Psicofármacos en Medicina Interna. I. Antidepresivos. Rev Invest Clin (Mex) 35, 247–256Google Scholar
de la Fuente, JRAlarcón-Segovia, D (1980) Depression as expressed in pre-Columbian Mexican art. Am J Psychiatry 137, 1095–1098Google ScholarPubMed
de la Fuente, JRBerlanda, C (1987) Evaluación y manejo de las depresiones resistentes con la combinación amitriptilina- isocarboxazida. Gac Méd Mex 123, 275–280Google Scholar
de la Fuente, JRBerlanga, CLeón, C (1986) Mania induced by tricyclic-MAOI combination therapy in bipolar treatment-resistant disorder. J Clin Psychiatry 47, 40–41Google ScholarPubMed
Horwath, EJohnson, JWeissman, Met al (1992) The validity of major depression with atypical features based on a community study. J Affective Disord 26, 117–126CrossRefGoogle ScholarPubMed
Spoov, JSouminen, JYLadhelma, RLet al (1993) Do reversed depressive symptoms occur together as a syndrome? J Affective Disord 27, 131–134CrossRefGoogle ScholarPubMed
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