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1228 – Regional Metabolic Brain Requirements Comparison In Selected Anxiety Disorders

Published online by Cambridge University Press:  15 April 2020

A. Grambal ,
J. Prasko ,
J. Horacek ,
J. Vyskocilova ,
Z. Grambalova  and
D. Kamaradova
A. Grambal
Affiliation:
Department of Psychiatry, Faculty of Medicine and Dentistry, University Palacky Olomouc, University Hospital Olomouc, Olomouc
J. Prasko
Affiliation:
Department of Psychiatry, Faculty of Medicine and Dentistry, University Palacky Olomouc, University Hospital Olomouc, Olomouc
J. Horacek
Affiliation:
Prague Psychiatric Centre, Charles University in Prague, Prague
J. Vyskocilova
Affiliation:
Faculty of Humanities, Charles University in Prague, Prague
Z. Grambalova
Affiliation:
Department of Neurology, Faculty of Medicine and Dentistry, University Palacky Olomouc, University Hospital Olomouc, Olomouc, Czech Republic
D. Kamaradova
Affiliation:
Department of Psychiatry, Faculty of Medicine and Dentistry, University Palacky Olomouc, University Hospital Olomouc, Olomouc

Abstract

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Introduction

Positron emission tomography (PET) detects indirect signs of higher or Loir neuronal activity and we suppose relation between the activity and the brain fiction. Though the anxiety disorders have many common characteristics, but there are also some differences. In our work we compare silent regional brain requirements in some anxiety disorders.

Method

Patients suffering from anxiety disorders were studied with 18FGD PET during rating state before systematic treatment. We studied 25 patients with agoraphobia, 21 with panic disorder, 40 with OCD and eleven with PTSD. Data were analyzed using SPM 99.

Results

There was higher uptake of FDG in patients suffering with OCD compared with PD and AP patients in left side basal ganglia. There was also higher uptake of FDG in patients with PD and AP compared with OCD in right frontal areas. The patients with OCD developer higher uptake compared with PTSD in middle temporal gyrus bilaterally. PTSD patients showed higher uptake of FDG in comparison of OCD in right anterior cingulate. There was higher uptake of FDG in PD an AP patients in comparison with PTSD patients in right inferior temporal gyrus.

Conclusion

There were differences in regional brain activities in FDG between various types of anxiety disorders.

Supported by IGA

MZ CR NT 11047-4/2010.

Type
Abstract
Information
European Psychiatry , Volume 28 , Issue S1: Abstracts of the 21th European Congress of Psychiatry , 2013 , 28-E594
Copyright
Copyright © European Psychiatric Association 2013
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