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Uso de midazolán para anestesia de la TEC: efectos sobre la eficacia antidepresiva y la duración de la crisis. Hallazgos preliminares

Published online by Cambridge University Press:  12 May 2020

M. Auriacombe ,
D. Grabot ,
P. M. Lincheneau ,
D. Zeiter  and
J. Tignol
M. Auriacombe
Affiliation:
Grupo de Investigación de la TEC, Laboratorio de Psiquiatría, Universidad de Burdeos II, Centro Carreire, Hospital Charles Perrens, Burdeos, Francia
D. Grabot
Affiliation:
Grupo de Investigación de la TEC, Laboratorio de Psiquiatría, Universidad de Burdeos II, Centro Carreire, Hospital Charles Perrens, Burdeos, Francia
P. M. Lincheneau
Affiliation:
Grupo de Investigación de la TEC, Laboratorio de Psiquiatría, Universidad de Burdeos II, Centro Carreire, Hospital Charles Perrens, Burdeos, Francia
D. Zeiter
Affiliation:
Grupo de Investigación de la TEC, Laboratorio de Psiquiatría, Universidad de Burdeos II, Centro Carreire, Hospital Charles Perrens, Burdeos, Francia
J. Tignol
Affiliation:
Grupo de Investigación de la TEC, Laboratorio de Psiquiatría, Universidad de Burdeos II, Centro Carreire, Hospital Charles Perrens, Burdeos, Francia
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Resumen

Midazolán es una benzodiacepina de acción corta que se ha utilizado para anestesia de la terapia electroconvulsiva (TEC). El propósito de este estudio era determinar sí el midazolán utilizado con este propósito deterioraría la eficacia antidepresiva de la TEC. En un estudio de asignación aleatoria doble ciego se comparó midazolán con metohexital sobre la eficacia antidepresiva de la TEC bilateral, medida por la reducción en las puntuaciones de la Escala de Evaluación de la Depresión de Montgomery Asberg (MADRS) y la duración de la crisis. Se incluyeron 16 pacientes con trastorno depresivo mayor del DSM-III-R con melancolía. Midazolán y metohexital no diferían en sus efectos sobre la puntuación de la MADRS o la duración de la crisis; no se encontró correlación entre la duración de la crisis y la evolución de la depresión para ninguno de los dos grupos. Nuestros hallazgos preliminares no apoyan la afirmación de que no se deben utilizar benzodiacepinas durante la TEC bilateral.

Keywords

terapia electroconvulsivabenzodiacepinasmidazolánmetohexitaleficaciaduración de la crisisdepresióntécnica
Type
Informe de caso
Information
European Psychiatry (Ed. Española) , Volume 3 , Issue 1 , February 1996 , pp. 40 - 44
Copyright
Copyright © European Psychiatric Association 1996

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