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Autoanticuerpos antinucleares en relación con el trastorno afectivo bipolar y la terapia de litio

Published online by Cambridge University Press:  12 May 2020

B. Spivak ,
M. Radwan ,
P. Bartur ,
R. Mester  and
A. Weizman
B. Spivak
Affiliation:
Unidad de Investigación, Hospital Psiquiátrico de Ness Ziona, Ness Ziona
M. Radwan
Affiliation:
Hospital Psiquiátrico Geha, Centro Médico Beilinson, Facultad Sackler de Medicina, Universidad de Tel Aviv, Tel Aviv
P. Bartur
Affiliation:
Laboratorio de Inmunología Clínica, Centro de Laboratorios Zamenhoff, Tel Aviv
R. Mester
Affiliation:
Unidad de Investigación, Hospital Psiquiátrico de Ness Ziona, Ness Ziona
A. Weizman
Affiliation:
Laboratorio de Psiquiatría Biológica, Centro de Investigación Médica Felsenstein, Centro Médico Beilinson, y Unidad de Investigación, Hospital Psiquiátrico de Geha, Facultad Sackler de Medicina, Universidad de Tel Aviv, Tel Aviv, Israel
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Resumen

Investigamos la presencia de anticuerpos antinucleares (ANA) en 63 pacientes bipolares sin medicación y tratados con litio en comparación con 37 controles sanos. Se detectó una mayor frecuencia de ANA positivos en pacientes bipolares en comparación con los controles (19% frente a 5%, respectivamente, P < 0,05). Este resultado no estaba relacionado con el tratamiento de litio. No se detectaron anticuerpos anti-DNA nativo o anticuerpos reactivos a antihistona entre los sujetos positivos a ANA.

Keywords

trastorno afectivo bipolarlitioanticuerpos antinucleares (ANA)autoinmunidad
Type
Comunicación breve
Information
European Psychiatry (Ed. Española) , Volume 3 , Issue 3 , June 1996 , pp. 203 - 206
Copyright
Copyright © European Psychiatric Association 1996

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