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Adición de sulpirida a la clozapina en pacientes esquizofrénicos resistentes al tratamiento: un estudio preliminar de una serie clínica

Published online by Cambridge University Press:  12 May 2020

R. Shiloh ,
Z. Zemishlany ,
D. Aizenberg  and
A. Weizman
R. Shiloh
Affiliation:
Hospital Psiquiátrico Geha, Petah Tikva y Facultad Sackler de Medicina, Centro de Investigación Médica Felsenstein, Universidad de Tel Aviv, Tel Aviv, Israel
Z. Zemishlany
Affiliation:
Hospital Psiquiátrico Geha, Petah Tikva y Facultad Sackler de Medicina, Centro de Investigación Médica Felsenstein, Universidad de Tel Aviv, Tel Aviv, Israel
D. Aizenberg
Affiliation:
Hospital Psiquiátrico Geha, Petah Tikva y Facultad Sackler de Medicina, Centro de Investigación Médica Felsenstein, Universidad de Tel Aviv, Tel Aviv, Israel
A. Weizman
Affiliation:
Hospital Psiquiátrico Geha, Petah Tikva y Facultad Sackler de Medicina, Centro de Investigación Médica Felsenstein, Universidad de Tel Aviv, Tel Aviv, Israel
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Resumen

Seis pacientes esquizofrénicos crónicos resistentes a los neurolépticos, que respondían parcialmente a la clozapina, recibieron conjuntamente de manera abierta durante 10 semanas 600 mg/día de sulpirida (un antagonista dopaminérgico selectivo del D 2) com o aumento al tratamiento con clozapina (un bloqueador relativamente débil del D 2). Se observó una notable reducción en los síntomas positivos y negativos en cuatro de los seis pacientes.

Keywords

esquizofreniaclozapinasulpiridadopaminaprolactina
Type
Informe clínico
Information
European Psychiatry (Ed. Española) , Volume 4 , Issue 7 , October 1997 , pp. 476 - 479
Copyright
Copyright © European Psychiatric Association 1997

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