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Correlaciones Entre Potenciales Evocados Auditivos Estándar y Síntomas en un Grupo de 50 Pacientes Esquizofrénicos

Published online by Cambridge University Press:  12 May 2020

T. Bougerol ,
A. Benraiss  and
J. C. Scotto
T. Bougerol
Affiliation:
Departamento de Psiquiatría Adulta, Hospital Santa Margarita, Marsella, F13294Francia
A. Benraiss
Affiliation:
Departamento de Psiquiatría Adulta, Hospital Santa Margarita, Marsella, F13294Francia
J. C. Scotto
Affiliation:
Departamento de Psiquiatría Adulta, Hospital Santa Margarita, Marsella, F13294Francia
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Resumen

Se registraron los potenciales evocados auditivos (AEPs) estándar en 50 pacientes esquizofrénicos y 47 controles normales. Todos los pacientes recibieron calificaciones en la Escala de Evaluación Psiquiátrica Breve (BPRS), la Escala para la Evaluación de Síntomas Negativos (SANS), la Escala para la Evaluación de Síntomas Positivos (SAPS) y la Escala del Síndrome Positivo y Negativo (PANSS), y fueron clasificados en tres grupos (pacientes de tipo positivo [n = 10], de tipo negativo [n = 23] y de tipo mixto [n = 17]) según los criterios normativos propuestos por Kay. Las latencias medias de los componentes de los AEPs (NI, P2, N2) y las amplitudes medias entre picos (N1P2, P2N2) no correlacionaban con la edad, la duración de la enfermedad, la duración de la hospitalización o la dosis de neurolépticos. La respuesta evocada no difería entre los tres grupos de pacientes (positivos, negativos y mixtos). Había sólo una tendencia (P = 0,075) a una latencia mayor del componente NI en el grupo de tipo negativo y a una más corta en el grupo de tipo positivo que en los de tipo mixto y de control. La latencia del componente N1 correlacionaba significativamente con los síntomas negativos de la esquizofrenia (las puntuaciones de la SANS). Esta correlación estaba relacionada con la gravedad de una dimensión depresiva del trastorno reflejada por el “factor depresivo” de la BPRS o las subescalas de “aplanamiento afectivo” y “abulia-apatía” de la SANS.

Keywords

potencial evocadoesquizofreniadepresión
Type
Artículo original
Information
European Psychiatry (Ed. Española) , Volume 5 , Issue 5 , June 1998 , pp. 309 - 318
Copyright
Copyright © European Psychiatric Association 1998

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