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Cambios inmunológicos en un caso de enfermedad de Marchiafava-Bignami: respuesta al tratamiento con amineptina

Published online by Cambridge University Press:  12 May 2020

T. Humbert
Affiliation:
Servicio de Psiquiatría, Hospital de Ales, 30100 Alé's en Cévennes
J.P. Bureau
Affiliation:
Laboratorio de Biología Celular y de Inmunogenética, Facultad de Medicina, 34000Montpellier
P. Chabrand
Affiliation:
Servicio de Psiquiatría, Hospital de Nímes, 30000Nîmes, Francia
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Resumen

La enfermedad de Marchiafava-Bignami (EMB) es una complicación poco frecuente del alcoholismo crónico. Describimos una forma regresiva de EMB en la que un tratamiento con amineptina mejoró una disminución primaria de células CD4+. No se observaron cambios significativos en el cociente CD4:CD8 en un pequeño número de sujetos con depresión mayor que recibieron este fármaco.

Type
Informe de caso
Copyright
Copyright © European Psychiatric Association 1995

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References

Bibliografía

Alavi, A, Hirschj, LJ. Studies of central nervous system disorders with single-photon emission computed tomography and positron emission tomography: evolution over the past 2 decades. Semin Nucl Med 1991; 21: 5881.CrossRefGoogle ScholarPubMed
Bagasra, O, Forman, L. Functionnal analysis of lymphocyte subpopulations in experimental cocaine abuse. I. Dose dependent activation of lymphocyte subsets. Clin Exp Immunol 1989; 77: 289–93.Google Scholar
Barnéoud, P, Neveu, PJ, Vitiello, S, Mormède, P, Le Moal, M. Brain neocortex immunomodulation in rats. Brain Res 1988; 474: 394–8.CrossRefGoogle ScholarPubMed
Baron, R, Heuser, K, Marioth, G. Marchiafava-Bignami disease with recovery diagnosed by CT and MRI: demyelisation affects several CNS structures. J Neurol 1989; 236: 364–6.CrossRefGoogle Scholar
Bourrat, C, Tomassi, M, Bochu, M, Kopp, N, Malsch, S. X-ray scanning in Marchiafava-Bignami disease. Rev Neurol 1984; 140: 426–31.Google ScholarPubMed
Delangre, T, Hannequin, D, Clavier, E, Denis, P, Mihout, B, Samson, M. Maladie de Marchiafava-Bignami d'évolution favorable. Rev Neurol 1986; 142: 933–6.Google Scholar
Delay, J, Brion, S, Escourolle, R, Sánchez, A. Rapports entre la dégénérescence du corps callux de Marchiafava- Bignami et la sclérose laminaire corticale de Morel (à propos de 5 observations anatomo-cliniques). Encéphale 1959; 4: 281311.Google Scholar
De Micco, C,-Toga, M. Le statut immunitaire du système nerveux central. Rev Neurol 1988; 144: 776–88.Google Scholar
Evans, DL, Pedersen, CA, Folds, JD. Major depression and immunity: preliminary evidence of decreased natural killer cell populations. Prog Neuropsychopharmacol Biol Psychiatry 1988; 12: 739–48.CrossRefGoogle ScholarPubMed
Ferguson, RM, Schmidtke, JR, Simmons, RL. In: Bergsma, D, Goldstein, A, eds. Neurochimical and Immunological Components of Schizophrenia. New York: Alan R Liss, 1978; 18: 379402.Google Scholar
Heepe, P, Nemeth, L, Brune, F, Grant, JW, Kleihues, P. Marchiafava-Bignami disease. A correlative computed tomography and morphological study. Eur Arch Psychiatr Neurol Sci 1988; 237: 74–9.CrossRefGoogle ScholarPubMed
Humbert, T, De Guilhermier, P, Maktouf, C, Grasset, G, López, FM, Chabrand, P. Marchiafava-Bignami disease. A case studied by structural and functional brain imaging. Eur Arch Psychiatry Clin Neurosa 1992; 242: 6971.CrossRefGoogle ScholarPubMed
Irwin, M, Caldwell, C, Smith, TL, Brown, S, Schuckit, MA, Gillin, JC. Major depressive disorder, alcoholism, and reduced natural killer cell cytotoxicity. Arch Gen Psychiatry 1990; 47: 713–9.CrossRefGoogle ScholarPubMed
Kempinsky, WH. Experimental study of distant effects of acute focal brain injury. A study of diaschisis. Arch Neurol Psychiatry 1958; 79: 376–89.CrossRefGoogle ScholarPubMed
Leboyer, M, Osherson, DN, Nosten, M, Roubertoux, P. Is autism associated with anomalous dominance? J Autism Dev Disord 1988; 18: 539–49.CrossRefGoogle ScholarPubMed
Marchiafava, E, Bignami, A. Sopra un alterzione del corpo calloso osservata in sogetti alcoolisti. Riv PatolNervMent 1903; 8: 544–9.Google Scholar
Meuer, SC, Schlossmann, SF, Reinherz, EL. Clonal analysis of human cytotoxic T lymphocytes: T4+ and T8+ effector T cells recognize producís of different major histocompatibility complex regions. Proc Nati Acad Sci USA 1982; 79: 4395–9.CrossRefGoogle Scholar
Meyrignac, C, Bokobza, M, Cesaro, P, Degos, JD. Contribution de l'image par résonance magnétique au diagnostic de la maladie de Marchiafava-Bignami. Presse Medícale 1987; 16: 1863–4.Google Scholar
Neveu, PJ. Cerebral neocortex modulation of immune functions. Life Sci 1988; 42: 1917–23.CrossRefGoogle ScholarPubMed
Neveu, PJ. Latéralisation cérébrale et réponse immunitaire. L'Encéphale 1989; XV: 405–8.Google Scholar
Ou, DD, Shen, ML, Luo, YD. Effects of cocaine on the immune system of Balc/C mice. Clin Immunol Immunopathol 1989; 52: 305–12.CrossRefGoogle Scholar
Schleifer, SJ, Keller, SE, Bond, RN, Cohen, J, Stein, M. Major depressive disorder and immunity. Arch Gen Psychiatry 1989; 46: 81–7.CrossRefGoogle ScholarPubMed
Warren, RP, Margaretten, NC, Pace, NC. Immune abnormalities in patients with autism. J Autism Dev Disord 1986; 16: 189–97.CrossRefGoogle ScholarPubMed
Wik, G, Borg, S, Sjorgen, I. Positron emission tomography determination of regional cerebral glucose metabolism in alcohol-dependent men and healthy controls using “C-glucose. Acta Psychiatr Scand 1988; 78: 234–41.Google ScholarPubMed