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Propofol–remifentanil-based anaesthesia vs. sevoflurane–fentanyl-based anaesthesia for immediate postoperative ophthalmic evaluation following strabismus surgery

Published online by Cambridge University Press:  04 April 2006

V. G. Yazbeck-Karam
Affiliation:
Rizk Hospital, Department of Anesthesiology, Beirut, Lebanon American University of Beirut, Medical Centre, Department of Anesthesiology, Beirut, Lebanon
M. T. Aouad
Affiliation:
American University of Beirut, Medical Centre, Department of Anesthesiology, Beirut, Lebanon
J. H. Bleik
Affiliation:
Rizk Hospital, Department of ophthalmology, Beirut, Lebanon
A. S. Baraka
Affiliation:
American University of Beirut, Medical Centre, Department of Anesthesiology, Beirut, Lebanon
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Abstract

Summary

Background and objective: Following strabismus surgery, immediate postoperative ophthalmic evaluation may be desired. Thus, an anaesthetic technique allowing rapid recovery of ocular motility is required. Saccadic eye movements is a biophysical monitor of ocular motility and may be used to assess recovery from anaesthesia. The aim of this study is to compare the time to the recovery of saccadic eye movements in patients, following one of two anaesthetic techniques: Propofol–remifentanil-based anaesthesia vs. sevoflurane–fentanyl-based anaesthesia. Methods: Fifty adult patients undergoing strabismus surgery were randomly assigned to one of two groups: patients in Group R received induction and maintenance of anaesthesia with propofol and remifentanil, while patients in Group S received induction of anaesthesia with propofol and fentanyl and maintenance of anaesthesia with sevoflurane. Recovery from anaesthesia was measured from the time all anaesthetics were turned off and was assessed every 2 min. Recovery time was attained when patients were able to generate brisk saccadic eye movements. At recovery time, the ophthalmic evaluation was started. Results: The mean recovery time of saccadic eye movements was significantly shorter in the Group R when compared to the Group S (12.1 ± 4.3 min vs. 21.5 ± 4.7 min, respectively, P < 0.0001). More patients in Group S experienced nausea and vomiting postoperatively as compared to Group R (9/25 vs. 2/25, respectively, P = 0.037). Conclusions: Propofol–remifentanil-based anaesthesia may be a useful technique in strabismus surgery when immediate postoperative ophthalmic evaluation is desired. When compared to sevoflurane maintenance of anaesthesia, it allows for a more rapid recovery from anaesthesia as judged by recovery of saccadic eye movements and a decreased incidence of postoperative nausea and vomiting.

Type
Original Article
Copyright
2006 European Society of Anaesthesiology

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References

Metz HS. Adjustable suture strabismus surgery. Ann Ophtalmol 1979; 11: 15931597.Google Scholar
Scott WE, Martin-Casals A, Jackson OB. Adjustable sutures in strabismus surgery. J Pediatr Ophthalmol 1977; 14: 7175.Google Scholar
Velez FG, Chan TK, Vives Tet al. Timing of postoperative adjustment in adjustable suture strabismus surgery. JAAPOS 2001; 5: 178183.Google Scholar
Ward JB, Niffenegger AS, Lavin CWet al. The use of propofol and mivacurium anesthetic technique for the immediate postoperative adjustment of sutures in strabismus surgery. Ophthalmology 1995; 102: 122128.Google Scholar
Ohmi G, Hosohata J, Okada AA, Fujikado T, Tanahashi N, Uchida I. Strabismus surgery using the intraoperative adjustable suture method under anesthesia with propofol. Jpn J Ophtalmol 1999; 43: 522525.Google Scholar
Rubsam B, Schafer WD, Schutle B, Roewer N. Preliminary report: analgesia with remifentanil for complicated eye muscle surgery. Strabismus 2000; 8: 287289.Google Scholar
Cogen MS, Guthrie ME, Vinik HR. The immediate postoperative adjustment of sutures in strabismus surgery with comaintenance of anesthesia using propofol and midazolam. JAAPOS 2002; 6: 241245.Google Scholar
Bleik JH, Yazbeck-Karam V. Comparison of the immediate with the 24-hour postoperative prism and cover measurements in adjustable muscle surgery. Is immediate postoperative adjustment reliable? JAAPOS 2004; 8: 528533.Google Scholar
Rossiter JD, Wood M, Lockwood A, Lewis K. Operating conditions for ocular surgery under general anaesthesia: an eccentric problem. Eye 2006; 20: 5558.Google Scholar
Patil BB, Dowd TC. Ocular physiology. In: Kumar C, Dodds C, Fanning G, eds. Ophthalmic Anaesthesia.Lisse, The Netherlands: Swets and Zeitlinger publishers, 2002: 2335.
Laborit G, Angiboust R, Papin JP. Monitoring the integrity of saccadic eye movements as a test of post-anaesthetic recovery (in French). Rev EEG Neurophysiol Clin 1977; 7: 7075.Google Scholar
Khan OA, Taylor SR, Jones JG. Anaesthesia and saccadic eye movements. Anaesthesia 2000; 55: 877882.Google Scholar
Paut O, Vercher JL, Blin Oet al. Evaluation of saccadic eye movements as an objective test of recovery from anaesthesia. Acta Anaesthesiol Scand 1995; 39: 11171124.Google Scholar
Gao F, Mapleson WW, Vickers MD. Effect of subanesthetic infusions of propofol on peak velocity of saccadic eye movement. Eur J Anaesthesiol 1991; 8: 267276.Google Scholar
Aantaa R. Assessment of the sedative effects of dexmedetomidine, an alpha 2-adrenoceptor agonist, with analysis of saccadic eye movements. Pharmacol Toxicol 1991; 68: 394398.Google Scholar
Yoshizumi J, Marshall RW, Vickers MD. Effects of low concentrations of cyclopropane and halothane on peak velocity of saccadic eye movement. Br J Anaesth 1991; 67: 735740.Google Scholar
Yoshizumi J, Marshall RW, Sanders LD, Vickers MD. Effects of small concentrations of isoflurane on some psychometric measurements. Br J Anaesth 1993; 71: 839844.Google Scholar
Nouraei SA, De Pennington N, Jones JG, Carpenter RH. Dose-related effect of sevoflurane sedation on higher control of eye movements and decision making. Br J Anaesth 2003; 91: 175183.Google Scholar
Carpenter RH, Descamps MJ, Morley CH, Leary TS, Jones JG. The effect of low dose sevoflurane on saccadic eye movement latency. Anaesthesia 2002; 57: 855859.Google Scholar
O'Hare RA, Mirakhur RK, Reid JE, Breslin DS, Hayes A. Recovery from propofol anaesthesia supplemented with remifentanil. Br J Anaesth 2001; 86: 361365.Google Scholar
Hackner C, Detsch O, Schneider G, Jelen-Esselborn S, Kochs E. Early recovery after remifentanil-pronounced compared with propofol-pronounced total intravenous anaesthesia for short painful procedures. Br J Anaesth 2003; 91: 580582.Google Scholar
Montes FR, Trillos JE, Rincon IE. Comparison of total intravenous anesthesia and sevoflurane–fentanyl anesthesia for outpatient otorhinolayngeal surgery. J Clin Anesth 2002; 14: 324328.Google Scholar
Madan R, Bhatia A, Chakithandy Set al. Prophylactic dexamethasone for postoperative nausea and vomiting in pediatric strabismus surgery: a dose ranging and safety evaluation study. Anesth Analg 2005; 100: 16221626.Google Scholar
Treschan TA, Zimmer C, Nass C, Stegen B, Esser J, Peters J. Inspired oxygen fraction of 0.8% does not attenuate postoperative nausea and vomiting after strabismus surgery. Anesthesiology 2005; 103: 610.Google Scholar
Lerman J. Surgical and patient factors involved in postoperative nausea and vomiting. Br J Anaesth 1992; 69: 24S32S.Google Scholar
Chhabra A, Pandey R, Khandelwal M, Subramaniam R, Gupta S. Anesthetic techniques and postoperative emesis in pediatric strabismus surgery. Reg Anesth Pain Med 2005; 30: 4347.Google Scholar
Tramer M, Moore A, Mc Quay H. Meta-analytic comparison of prophylactic antiemetic efficacy for postoperative nausea and vomiting: propofol anaesthesia vs. omitting nitrous oxide versus total intravenous anaesthesia with propofol. Br J Anaesth 1997; 78: 256259.Google Scholar
Standl T, Wilhelm S, von Knobelsdorf G, Schulte AM, Esch J. Propofol reduces emesis after sufentanil supplemented anaesthesia in pediatric squint surgery. Acta Anaesth Scand 1996; 40: 729733.Google Scholar
Apfel CC, Bacher A, Biedler Aet al. A factorial trial of six interventions for the prevention of postoperative nausea and vomiting (in German). Anaesthesist 2005; 54: 201209.Google Scholar
Biallas R, Rusch D, de Decker W, Wulf H, Siebrecht D, Scholz J. Prophylaxis of postoperative nausea and vomiting (PONV) in children undergoing strabismus surgery. Sevoflurane/N2O plus dimenhydrinate vs. propofol/ remifentanil plus dimenhydrinate (in German). Anaesthesist 2003; 52: 586595.Google Scholar
Apfel CC, Kranke P, Katz MHet al. Volatile anaesthetics may be the main cause of early but not delayed postoperative vomiting: a randomized controlled trial of factorial design. Br J Anaesth 2002; 88: 659668.Google Scholar
Van den Berg AA, Lambourne A, Claybourn PA. The oculo-emetic reflex, a rationalization of post ophthalmic anaesthesia vomiting. Anaesthesia 1989; 44: 110117.Google Scholar