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Pressure support ventilation during inhalational induction with sevoflurane and remifentanil in adults

Published online by Cambridge University Press:  13 October 2005

F. Banchereau ,
Y. Herve ,
A. Quinart  and
A.-M. Cros
F. Banchereau
Affiliation:
Université Victor Segalen-Bordeaux II, Hôpital Pellegrin Enfants, DAR IV, Bordeaux, France
Y. Herve
Affiliation:
Université Victor Segalen-Bordeaux II, Bordeaux, France
A. Quinart
Affiliation:
Hôpital d'Instruction des Armées Robert Picqué, Département d'Anesthésie Réanimation, Hôpital Pellegrin, DAR I, Bordeaux, France
A.-M. Cros
Affiliation:
Université Victor Segalen-Bordeaux II, Hôpital Pellegrin Enfants, DAR IV, Bordeaux, France
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Summary

Background and objective: The purpose of this prospective randomized study was to assess the value of pressure support ventilation during inhalational induction with sevoflurane in adult patients. Methods: Thirty-five adult patients, ASA I–II and scheduled for ear nose throat surgery were studied. Vital capacity induction with 8% sevoflurane in 8 L min−1 oxygen was performed. Pressure support ventilation was used in Group 1 with pressure set at 15 cmH2O. In Group 2, patients breathed spontaneously. After 2 min, sevoflurane was set to 3% and remifentanil 1 μg kg−1 was injected over 2 min followed by an infusion of 0.1μg kg−1 min−1. Two minutes after the end of the bolus, intubation was performed. Bispectral index, oxygen saturation, respiratory rate, end-tidal carbon dioxide, expired tidal volume and expired sevoflurane concentration were recorded every minute. Results: Eighteen patients were included in Group 1 and 17 in Group 2. Saturation, respiratory rate and end-tidal carbon dioxide were similar in the two groups. Expired tidal volume was significantly higher and bispectral index values significantly lower in Group 1. Intubating conditions were better in Group 1. Conclusions: Pressure support ventilation provides both better ventilation and deeper level of anaesthesia during inhalation induction with sevoflurane.

Keywords

ANAESTHESIA INHALATIONALSEVOFLURANEVENTILATION ARTIFICIAL, pressure supportOPIOID, remifentanil
Type
Original Article
Information
European Journal of Anaesthesiology , Volume 22 , Issue 11 , November 2005 , pp. 826 - 830
Copyright
© 2005 European Society of Anaesthesiology

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