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Optimal ventilator settings in acute lung injury and acute respiratory distress syndrome

Published online by Cambridge University Press:  01 February 2008

M. Yilmaz  and
O. Gajic
M. Yilmaz*
Affiliation:
Mayo Clinic College of Medicine, Division of Pulmonary and Critical Care Medicine, Rochester, MN, USA Akdeniz University, Medical Faculty, Department of Anaesthesiology and Intensive Care, Antalya, Turkey
O. Gajic
Affiliation:
Mayo Clinic College of Medicine, Division of Pulmonary and Critical Care Medicine, Rochester, MN, USA
*
Correspondence to: Murat Yilmaz, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. E-mail: [email protected]; Tel: +1 507 255 6051; Fax: +1 507 255 4267
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Summary

Despite recent advances in intensive care medicine, acute lung injury and its more severe form, acute respiratory distress syndrome pose major therapeutic problems. While mechanical ventilation is integral to the care of these patients, its adverse consequences including ventilator-induced lung injury are determinants of disease progression and prognosis. Among several important ventilator parameters, the use of low tidal volumes is probably the most important feature of lung-protective mechanical ventilation. Intensivists should be trained to recognize acute lung injury and acute respiratory distress syndrome and encouraged to use low-tidal-volume ventilation in clinical practice. Alternative modes of ventilation such as high-frequency ventilation and prone position should be reserved for selected patients in whom conventional lung-protective ventilation strategies have failed.

Keywords

RESPIRATION ARTIFICIALRESPIRATORY DISTRESS SYNDROME ADULTHIGH-FREQUENCY VENTILATIONCRITICAL CARE
Type
Review
Information
European Journal of Anaesthesiology , Volume 25 , Issue 2 , February 2008 , pp. 89 - 96
Copyright
Copyright © European Society of Anaesthesiology 2007

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