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Low flow desflurane and sevoflurane anaesthesia in children

Published online by Cambridge University Press:  23 December 2005

Y. Isik ,
S. Goksu ,
H. Kocoglu  and
U. Oner
Y. Isik
Affiliation:
University of Gaziantep, Faculty of Medicine, Department of Anesthesiology and Reanimation, Gaziantep, Turkey
S. Goksu
Affiliation:
University of Gaziantep, Faculty of Medicine, Department of Anesthesiology and Reanimation, Gaziantep, Turkey
H. Kocoglu
Affiliation:
Abant Izzet Baysal University, Izzet Baysal Medical Faculty, Department of Anesthesiology, Bolu, Turkey
U. Oner
Affiliation:
University of Gaziantep, Faculty of Medicine, Department of Anesthesiology and Reanimation, Gaziantep, Turkey
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Extract

Summary

Background and objective: Low flow desflurane and sevoflurane anaesthesia were administered to children and compared for haemodynamic response, renal and hepatic function, recovery time and postoperative nausea and vomiting. Methods: Eighty ASA I–II patients aged 5–15 yr were included in the study. Midazolam was given for premedication. Anaesthesia induction was performed with fentanyl, propofol and atracurium. After intubation, the first group received desflurane, oxygen and nitrous oxide at 6 L min−1 and the second sevoflurane, oxygen and nitrous oxide at 6L min−1. Ten minutes after induction the flow was decreased to 1L min−1 in both groups. Haemodynamic parameters, preoperative and postoperative renal and hepatic function, the times of operation and anaesthesia, and early recovery data were recorded. Modified Aldrete scores were noted at the 10th and 30th minutes postoperatively and postoperative nausea, and vomiting were assessed. Results: There were no significant differences in haemodynamic parameters, renal and hepatic functions, postoperative recovery and postoperative nausea and vomiting between groups. The recovery time was shorter in the desflurane group compared to the sevoflurane group. Conclusion: Low flow desflurane and sevoflurane anaesthesia do not adversely affect haemodynamic parameters, hepatic and renal function in children. Desflurane may be preferred when early recovery from anaesthesia is warranted.

Keywords

ANAESTHESIA INHALATION, desflurane, sevoflurane, low flowCHILDRENPOSTOPERATIVE RECOVERY PERIODPOSTOPERATIVE NAUSEA AND VOMITING
Type
Original Article
Information
European Journal of Anaesthesiology , Volume 23 , Issue 1 , January 2006 , pp. 60 - 64
Copyright
© 2006 European Society of Anaesthesiology

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References

Lerman J. Inhalational anesthetics. Paediatr Anesth 2004; 14: 380–383.Google Scholar
Baum JA. Low Flow Anaesthesia. The Theory and Practice of Low Flow, Minimal Flow and Closed system Anaesthesia, 2nd edn. Butterworth-Heinemann, Oxford 2001: 220–268.
Meakin GH. Low-flow anaesthesia in infants and children. Br J Anesth 1999; 83: 50–57.Google Scholar
Igarahsi M. Clinical evaluation of low flow sevoflurane anaesthesia for paediatric patients. Acta Anaesthesiol Scand 1999; 43: 19–23.Google Scholar
Aldrete JA. The post-anaesthesia recovery score revisited. J Clin Anesth 1995; 7: 89–91.Google Scholar
Lerman J. Sevoflurane in paediatric anaesthesia. Anesth Analg 1995; 81: 4–10.Google Scholar
Wissing H, Kuhn I. The effect of desflurane on liver function markers in infants and children. Acta Anaesthesiol Scand 2002; 44: 1149–1153.Google Scholar
Avramov MN, Griffin JD, White PF. The effect of fresh gas flow and anesthetic technique on the ability to control acute hemodynamic responses during surgery. Anesth Analg 1998; 87: 666–670.Google Scholar
Sponheim S, Skraastad O, Helseth E, Due-Tonnesen B, Aamodt G, Breivik H. Effects of 0.5 and 1.0 MAC isoflurane, sevoflurane and desflurane on intracranial and cerebral perfusion pressures in children. Acta Anaesthesiol Scand 2003; 47: 932–938.Google Scholar
Scheller MS. New volatile anesthetics: desflurane and sevoflurane. Semin Anesth 1992; 11: 114–122.Google Scholar
Frink EJ, Green Jr WB, Brown EA, Malcomson M, Hammond LC, Valencia FG et al. Compound A concentration during sevoflurane anaesthesia in children. Anesthesiology 1996; 84: 566–571.Google Scholar
Nishiyama T, Yokoyama T, Hanaoka K. Liver function after sevoflurane or isoflurane anaesthesia in neurosurgical patients. Can J Anaesth 1998; 45: 753–756.Google Scholar
Wissing H, Kuhn I. The effect of desflurane on liver function markers in infants and children. Acta Anaesthesiol Scand 2002; 44: 1149–1153.Google Scholar
Welborn LG, Hannallah RS, Norden JM, Ruttimann UE, Callan CM. Comparison of emergence and recovery characteristics of sevoflurane, desflurane, and halothane in paediatric ambulatory patients. Anesth Analg 1996; 83: 917–920.Google Scholar
Cohen IT, Finkel JC, Hannallah RS, Hummer KA, Patel KM. The effect of fentanyl on the emergence characteristics after desflurane or sevoflurane anaesthesia in children. Anesth Analg 2002; 94: 1178–1181.Google Scholar
Kuhn I, Scheifler G, Wissing H. Incidence of nausea and vomiting in children after strabismus surgery following desflurane anaesthesia. Paediatr Anaesth 1999; 9: 521–526.Google Scholar