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Exposure of personnel to sevoflurane during paediatric anaesthesia: influence of professional role and anaesthetic procedure

Published online by Cambridge University Press:  23 December 2004

A. Gentili ,
A. Accorsi ,
A. Pigna ,
V. Bachiocco ,
I. Domenichini ,
S. Baroncini  and
F. S. Violante
A. Gentili
Affiliation:
S. Orsola-Malpighi Hospital, Department of Paediatric Anaesthesia and Intensive Care, Bologna, Italy
A. Accorsi
Affiliation:
S. Orsola-Malpighi Hospital, Occupational Medicine Service, University of Bologna, Bologna, Italy
A. Pigna
Affiliation:
S. Orsola-Malpighi Hospital, Department of Paediatric Anaesthesia and Intensive Care, Bologna, Italy
V. Bachiocco
Affiliation:
S. Orsola-Malpighi Hospital, Department of Paediatric Anaesthesia and Intensive Care, Bologna, Italy
I. Domenichini
Affiliation:
S. Orsola-Malpighi Hospital, Safety, Hygiene and Occupational Medicine Service, Bologna, Italy
S. Baroncini
Affiliation:
S. Orsola-Malpighi Hospital, Department of Paediatric Anaesthesia and Intensive Care, Bologna, Italy
F. S. Violante
Affiliation:
S. Orsola-Malpighi Hospital, Occupational Health Unit, Bologna, Italy
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Abstract

Summary

Background and objective: This study was performed to determine the individual exposure of paediatric operating theatre personnel to sevoflurane and to evaluate the impact of inhalation induction and various airway approaches on exposure to airborne sevoflurane.

Methods: Mean individual environmental (workplace air) exposure to sevoflurane and a biomarker of exposure (urinary sevoflurane) were monitored in 36 subjects (10 anaesthetists, 10 surgeons, 12 nurses and 4 auxiliary personnel) working in two paediatric operating rooms.

Results: Environmental and urinary values were significantly greater in anaesthetists compared with other groups, with median values of 0.65 ppm (interquartile range 1.36; 95th percentile 4.36) for breathing zone sevoflurane and 2.1 μg L−1 urine (interquartile range 2.6; 95th percentile 7.6) for urinary sevoflurane. Anaesthetists exceeded the 2 ppm maximum allowed environmental concentration recommended by the National Institute for Occupational Safety and Health in 4 of 22 cases (18.1%). A positive correlation was found between the number of patients undergoing inhalational induction each day and mean values of breathing zone and urinary sevoflurane. An increase in the number of daily laryngeal mask insertions, or the use of rigid bronchoscopy, are statistically related to higher environmental and urinary values (P < 0.01 and <0.00001 for breathing zone sevoflurane, P < 0.05 and <0.01 for urinary sevoflurane, respectively).

Conclusions: Anaesthesia with sevoflurane can pose a hazard of chronic exposure with anaesthetists having the highest risk. Endotracheal intubation offers considerable protection against exposure. Routine anaesthesia using a standard facemask, a laryngeal mask or rigid bronchoscopy are risk factors for increased anaesthetic exposure.

Keywords

AIRWAY MANAGEMENT, tracheal tube, laryngeal mask, bronchoscopeANAESTHESIA, paediatricANAESTHETICS EXPOSUREMEASUREMENTANAESTHETICS, INHALATION, sevofluraneOPERATING ROOM, personnelTECHNIQUES
Type
Original Article
Information
European Journal of Anaesthesiology , Volume 21 , Issue 8 , August 2004 , pp. 638 - 645
Copyright
2004 European Society of Anaesthesiology

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