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Use of recombinant factor VIIa for major haemorrhage

Published online by Cambridge University Press:  29 June 2005

R. J. Pugh ,
R. Wenstone ,
V. J. Martlew  and
G. Marx
R. J. Pugh
Affiliation:
Department of Anaesthesia, Royal Liverpool University Hospital, Liverpool, UK Current address: Department of Anaesthesia, Countess of Chester Hospital, NHS Foundation Trust, Cheshire, UK
R. Wenstone
Affiliation:
Directorate of Intensive Care, Royal Liverpool University Hospital, Liverpool, UK
V. J. Martlew
Affiliation:
Department of Haematology, Royal Liverpool University Hospital, Liverpool, UK
G. Marx
Affiliation:
Department of Anaesthesia, University of Liverpool, Liverpool, UK Current address: Ltd. OA Intensivetherapie, Klinik f. Anästhesiologie und Intensivtherapie, Klinikum der Friedrich-Schiller-Universität Jena, Jena, Germany
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Type
Correspondence
Information
European Journal of Anaesthesiology , Volume 22 , Issue 7 , July 2005 , pp. 548 - 550
Copyright
© 2005 European Society of Anaesthesiology

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References

Rossaint R, Boffard KD, Warren BL et al. Decreased transfusion utilization using recombinant factor VIIa as an adjunct in trauma. Intens Care Med 2004; 30 (Suppl 1): S199.Google Scholar
Hedner U. NovoSeven as a universal haemostatic agent. Blood Coagul Fibrin 2000; 11 (Suppl 1): S107–S111.Google Scholar
Aggarwal A, Malkovska V, Catlett JP, Alcorn K. Recombinant activated factor VII (rFVIIa) as salvage treatment for intractable hemorrhage. Thromb J 2004; 2: 9.Google Scholar
Clark AD, Gordon WC, Walker ID, Tait RC. ‘Last-ditch’ use of recombinant factor VIIa in patients with massive haemorrhage is ineffective. Vox Sang 2004; 86: 120–124.Google Scholar
Meng ZH, Wolberg AS, Monroe III DM, Hoffman M. The effect of temperature and pH on the activity of factor VIIa: implications for the efficacy of high-dose factor VIIa in hypothermic and acidotic patients. J Trauma 2003; 55: 886–891.Google Scholar
Gallistl S, Cvirn G, Muntean W. Recombinant factor VIIa does not induce hypercoagulability in vitro. Thromb Haemost 1999; 81: 245–249.Google Scholar
Siegel LJ, Gerigk L, Tuttenberg J, Dempfle CE, Scharf J, Fiedler F. Cerebral sinus thrombosis in a trauma patient after recombinant activated factor VII infusion. Anesthesiology 2004; 100: 441–443.Google Scholar