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In-use contamination of propofol. A clinical study

Published online by Cambridge University Press:  12 September 2006

A. Bach ,
J. Motsch ,
H. Schmidt ,
B. W. Böttiger ,
H. Böhrer ,
E. Martin  and
H.-G. Sonntag
A. Bach
Affiliation:
Department of Anaesthesia, University Hospital and Institute of Medical Microbiology and Hygiene, Heidelberg, Germany
J. Motsch
Affiliation:
Department of Anaesthesia, University Hospital and Institute of Medical Microbiology and Hygiene, Heidelberg, Germany
H. Schmidt
Affiliation:
Department of Anaesthesia, University Hospital and Institute of Medical Microbiology and Hygiene, Heidelberg, Germany
B. W. Böttiger
Affiliation:
Department of Anaesthesia, University Hospital and Institute of Medical Microbiology and Hygiene, Heidelberg, Germany
H. Böhrer
Affiliation:
Department of Anaesthesia, University Hospital and Institute of Medical Microbiology and Hygiene, Heidelberg, Germany
E. Martin
Affiliation:
Department of Anaesthesia, University Hospital and Institute of Medical Microbiology and Hygiene, Heidelberg, Germany
H.-G. Sonntag
Affiliation:
Department of Anaesthesia, University Hospital and Institute of Medical Microbiology and Hygiene, Heidelberg, Germany
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Abstract

Reports about post-operative infections associated with the use of propofol prompted us to investigate the in-use contamination of lipid-formulated intravenous (i.v.) anaesthetics used for general anaesthesia or for sedation of intensive care patients in this department. The level and incidence of extrinsic contamination of propofol (‘Diprivan’) and of another intravenous anaesthetic, etomidate, formulated in lipid solution (‘Etomidat-lipuro’) was found to be low during two study periods. However, the need to observe strict aseptic precautions in handling these intravenous drugs must be emphasized.

Keywords

anaesthetics intravenouspropofoletomidatecomplicationsinfections
Type
Original Article
Information
European Journal of Anaesthesiology , Volume 14 , Issue 2 , March 1997 , pp. 178 - 183
Copyright
1997 European Society of Anaesthesiology

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