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Breath interval as a continuous measure of opioid effects of intravenous fentanyl and alfentanil

Published online by Cambridge University Press:  11 July 2005

J. A. Smart
Affiliation:
University Department of Anaesthesia, Glenfield Hospital and Leicester Royal Infirmary, Leicester, UK
E. J. Pallett
Affiliation:
University Department of Anaesthesia, Glenfield Hospital and Leicester Royal Infirmary, Leicester, UK
David J. R. Duthie
Affiliation:
University Department of Anaesthesia, Glenfield Hospital and Leicester Royal Infirmary, Leicester, UK
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Abstract

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Type
Correspondence
Copyright
© 2003 European Society of Anaesthesiology

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References

Smart JA, Pallett EJ, Duthie DJR. Breath interval as a measure of dynamic opioid effect. Br J Anaesth 2000; 84: 735738.Google Scholar
Goodman NW, Vanner RG, Wade JA. Effects of incremental alfentanil and propofol on the breathing of anaesthetised patients. Br J Anaesth 1989; 65: 548553.Google Scholar
Holford N. MKMODEL, 5th edn. Cambridge, UK: Biosoft, 1994.
Cheng H, Gillespie WR, Jusko WJ. Mean Residence Time concepts for non-linear pharmacokinetic systems. Biopharmaceut Drug Depos 1994; 15: 627641.Google Scholar
Ebling WF, Lee EN, Stanski DR. Understanding pharmacokinetics and pharmacodynamics through computer simulation: 1. The comparative clinical profiles of fentanyl and alfentanil. Anesthesiology 1990; 72: 650658.Google Scholar
Shafer SL, Varvel JR. Pharmacokinetics, pharmacodynamics and rational opioid selection. Anesthesiology 1991; 74: 5363.Google Scholar