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Published online by Cambridge University Press: 15 February 2011
Life science researches have been profoundly impacted by technological advances allowingfaster and cheaper DNA sequencing. Opening a wide range of applications in medical andbiology, the last generation sequencing platforms raised new challenges, in particular inprocessing, analysing and interpreting massive data. In this talk, the growing role ofbioinformatics will be illustrated by providing some figures about genome sequencing andothers applications aimed at unravelling biological mechanisms. Methods to gather insightsfrom massive amount of data will be illustrated by the genome annotation process, by whichgenes are identified in the genome sequence.