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Medical image – based computational model of pulsatile flowin saccular aneurisms

Published online by Cambridge University Press:  15 November 2003

Stéphanie Salmon ,
Marc Thiriet  and
Jean-Frédéric Gerbeau
Stéphanie Salmon
Affiliation:
UFR de Mathématique et d'Informatique, Université L. Pasteur, 67084 Strasbourg, France.
Marc Thiriet
Affiliation:
Projet INRIA “BANG” and Laboratoire Jacques-Louis Lions, CNRS UMR 7598, UPMC, 75252 Paris, France.
Jean-Frédéric Gerbeau
Affiliation:
INRIA, Projet BANG, BP 105, 78153 Le Chesnay, France. [email protected].
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Abstract

Saccular aneurisms, swelling of a blood vessel,are investigated in order (i) to estimate the development risk ofthe wall lesion, before and after intravascular treatment,assuming that the pressure is the major factor,and (ii) to better plan medical interventions.Numerical simulations, using the finite element method,are performed in three-dimensional aneurisms.Computational meshes are derived from medical imaging datato take into account both between-subject and within-subjectanatomical variability of the diseased vessel segment.The 3D reconstruction is associated with a faceted surface.A geometrical model is then obtained to be finally meshed for a finite element use. The pulsatile flow of incompressible Newtonian blood is illustrated by numerical simulations carried out in two saccular aneurism types, a side- and a terminal-aneurism.High pressure zones are observed in the aneurism cavity,especially in the terminal one.

Keywords

3D surface reconstructionfinite element methodmedical imagesmesh generationNavier–Stokes equations.
Type
Research Article
Information
ESAIM: Mathematical Modelling and Numerical Analysis , Volume 37 , Issue 4: Special issue on Biological and Biomedical Applications , July 2003 , pp. 663 - 679
Copyright
© EDP Sciences, SMAI, 2003

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