Hostname: page-component-78c5997874-mlc7c Total loading time: 0 Render date: 2024-11-19T23:49:05.310Z Has data issue: false hasContentIssue false
  • English
  • Français

Many more reasons behind difficulties in recruiting patients to randomized controlled trials in psychiatry

Published online by Cambridge University Press:  12 June 2013

C.E. Adams
C.E. Adams*
Affiliation:
Chair of Mental Health Services Research, Co-ordinating Editor Cochrane Schizophrenia Group, University of Nottingham, UK
*
Address for correspondence: C.E. Adams, Institute of Mental Health, University of Nottingham Innovation Park, Jubilee Campus, Triumph Road, Nottingham NG7 2TU, UK. (Email: [email protected])
Get access Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'

Keywords

Evidence-based psychiatrymental healthrandomized controlled trialsresearch governance
Type
Commentaries
Information
Epidemiology and Psychiatric Sciences , Volume 22 , Issue 4 , December 2013 , pp. 321 - 323
Copyright
Copyright © Cambridge University Press 2013 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Creative Commons (2013). All Trials Registered/All Results Reported. Retrieved 17 April 2013 from http://www.alltrials.net/Google Scholar
Duley, L, Antman, K, Arena, J, Avezum, A, Blumenthal, M, Bosch, J, Chrolavicius, S, Li, T, Ounpuu, S, Perez, AC, Sleight, P, Svard, R, Temple, R, Tsouderous, Y, Yunis, C, Yusuf, S (2008). Specific barriers to the conduct of randomized trials. Clinical Trials 5, 40–48.CrossRefGoogle Scholar
Goldacre, B (2012). Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients. Fourth Estate: London.Google Scholar
Hayden, EC (2012). Informed consent: a broken contract. Nature 486, 312–314.CrossRefGoogle ScholarPubMed
Leeson, VC, Tyrer, P (2013) The advance of research governance in psychiatry: one step forward, two steps back. Epidemiology and Psychiatric Sciences, in press.CrossRefGoogle ScholarPubMed
Lloyd, K, White, J (2011). Democratizing clinical research. Nature 474, 277–278.CrossRefGoogle ScholarPubMed
Lloyd, K, White, J, Chalmers, I (2012). Schizophrenia: patients' research priorities get funded. Nature 487, 432.CrossRefGoogle ScholarPubMed
Roberts, I, Prieto-Merino, D, Shakur, H, Chalmers, I, Nicholl, J (2011). Effect of consent rituals on mortality in emergency care research. Lancet 377, 1071–1072.CrossRefGoogle ScholarPubMed
Savulescu, J, Chalmers, I, Blunt, J (1996). Are research ethics committees behaving unethically? Some suggestions for improving performance and accountability. British Medical Journal 313, 1390–1393.CrossRefGoogle ScholarPubMed
Thorpe, KE, Zwarenstein, M, Oxman, AD, Treweek, S, Furberg, CD, Altman, DG, Tunis, S, Bergel, E, Harvey, I, Magid, DJ, Chalkidou, K (2009). A pragmatic-explanatory continuum indicator summary (PRECIS): a tool to help trial designers. Journal of Clinical Epidemiology 62, 464–475.CrossRefGoogle ScholarPubMed
Tosh, G, Soares-Weiser, K, Adams, CE (2011). Pragmatic vs explanatory trials: the Pragmascope tool to help measure differences in protocols of mental health randomized controlled trials. Dialogues in Clinical Neuroscience 13, 209–215.CrossRefGoogle ScholarPubMed
Treweek, S, Lockhart, P, Pitkethly, M, Cook, JA, Kjeldstrøm, M, Johansen, M, Taskila, TK, Sullivan, FM, Wilson, S, Jackson, C, Jones, R, Mitchell, ED (2013). Methods to improve recruitment to randomised controlled trials: Cochrane systematic review and meta-analysis. British Medical Journal Open 3, 2 DOI: i10.1136/bmjopen-2012-002360.Google ScholarPubMed