Hostname: page-component-78c5997874-t5tsf Total loading time: 0 Render date: 2024-11-05T03:55:13.076Z Has data issue: false hasContentIssue false
  • English
  • Français

Viruses in acute gastroenteritis in children in Pune, India

Published online by Cambridge University Press:  15 May 2009

P. Bright Singh ,
M. A. Sreenivasan  and
Khorshed M. Pavri
P. Bright Singh
Affiliation:
National Institute of Virology, 20-A, Dr Ambedkar Road, Pune-411 001, India
M. A. Sreenivasan
Affiliation:
National Institute of Virology, 20-A, Dr Ambedkar Road, Pune-411 001, India
Khorshed M. Pavri
Affiliation:
National Institute of Virology, 20-A, Dr Ambedkar Road, Pune-411 001, India
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

A 2-year study from January 1981 to December 1982 was undertaken to determine the role of viruses in the causation of diarrhoea in hospitalized children in Pune, Maharashtra State, India. The stool samples of 426 children (213 diarrhoeal and 213 non-diarrhoeal controls) were investigated by electron microscopy and ELISA for the presence of viruses. Six morphologically distinct viruses were visualized: rotavirus, coronavirus-like particles (CVLP), adenovirus, astrovirus, calicivirus and small round virus-like particles (SRV). Rotavirus was detected in 28·6% of the diarrhoea! patients and in 1·4 % of the controls. The frequency of infection with rotavirus was highest in the children aged less than 5 years. The mean age of rotavirus-positive patients was 11 months. Although rotavirus was detected in almost every month, there has a seasonal trend for colder months when CVLP cases were fewest. However, the prevalence of CVLP was greater in the control group (23–0%) rather than in those with diarrhoea (8–9%). In the control group, CVLP were detected more frequently during the summer months. An inverse relationship between CVLP and rotavirus was observed in children. Adenovirus, astrovirus, calicivirus and SRV were detected in a small proportion of children with and without clinical symptoms of gastroenteritis.

Type
Research Article
Information
Epidemiology & Infection , Volume 102 , Issue 2 , April 1989 , pp. 345 - 353
Copyright
Copyright © Cambridge University Press 1989

References

REFERENCES

Beards, G. M., Campbell, A. D., Cottrell, N. R., Peiris, J. S. M., Rees, N., Sanders, R. C., Shirley, J. A., Wood, H. C. & Flewett, T. H. (1984). Enzyme linked immunosorbent assays based on polyclonal and monoclonal antibodies for rotavirus detection Journal of Clinical Microbiology 19, 248–256.CrossRefGoogle ScholarPubMed
Holmes, I. H., Mathan, M., Albert, M. J., Swaminathan, S. P., Maiya, P. P., Pereira, S. M. & Baker, S. J. (1974). Orbiviruses and gastroenteritis. Lancet 2, 658–659.CrossRefGoogle ScholarPubMed
Madeley, C. R. & Cosgrove, B. P. (1975). Viruses in infantile gastroenteritis. Lancet 2, 124.CrossRefGoogle ScholarPubMed
Madeley, C. R. & Cosgrove, B. P. (1976). Calicivirus in man. Lancet 1, 199–200.CrossRefGoogle Scholar
Madeley, C. R., Cosgrove, B. P., Bell, E. J. & Fallon, R. J. (1977). Stool viruses in babies in Glasgow. 1. Hospital admissions with diarrhoea. Journal of Hygiene, 78, 261–273.CrossRefGoogle Scholar
Maiya, P. P., Pereira, S. M., Mathan, M., Bhat, P., Albert, M. J. & Baker, S. J. (1977).Aetiology of acute gastroenteritis in infancy and early childhood in Southern India. Archives of Diseases in Childhood 52, 482–485.CrossRefGoogle ScholarPubMed
Mathan, M., Mathan, V. I., Swaminathan, S. P., Yesudoss, S. & Baker, S. J. (1975). Pleomorphic virus-like particles in human faeces. Lancet 1, 1068–1069.CrossRefGoogle ScholarPubMed
Panikar, C. K. J., Mathew, S. & Mathan, M. (1982). Rotavirus and acute diarrhoeal disease in children in a Southern Indian coastal town. Bulletin of the World Health Organization 60, 123–127.Google Scholar
Schnagl, R. D., Holmes, I. H. & Mackay-Scollay, E. M. (1978). Coronavirus-like particles in aboriginals and non-aboriginals in Western Australia. Medical Journal of Australia 1, 307–309.CrossRefGoogle ScholarPubMed
Sitbon, M. (1985). Human enteric coronavirus-like particles (CVLP) with different epidemiological characteristics. Journal of Medical Virology 16, 67–76.CrossRefGoogle Scholar