Hostname: page-component-78c5997874-4rdpn Total loading time: 0 Render date: 2024-11-02T20:05:28.375Z Has data issue: false hasContentIssue false
  • English
  • Français

Transferable resistance to trimethoprim in enteric pathogens isolated in Kuwait

Published online by Cambridge University Press:  19 October 2009

T. D. Chugh
T. D. Chugh
Affiliation:
Faculty of Medicine, University of Kuwait, P.O. Box 24923, Kuwait
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Trimethoprim resistance was seen in 14·8% of 500 strains of salmonella, 43·1% of 153 strains ofshigella and 59% of 27 strains of Escherichia coli isolated from stools of patients with diarrhoea. Strains with a high level of trimethoprim resistance (MIC of ≥ 512 μg) were subjected to conjugal transfer. Trimethoprim resistance was plasmid-mediated in all of 42 strains of shigella and 12 strains of E. coli examined. However, 2 of the 47 strains of salmonella could not transfer their trimethoprim resistance either directly or by mobilization with the transfer factors X and Δ both at 37 and 25 °C overnight incubation.

Type
Research Article
Information
Journal of Hygiene , Volume 95 , Issue 2 , October 1985 , pp. 391 - 395
Copyright
Copyright © Cambridge University Press 1985

References

REFERENCES

Anderson, D. M. (1980). Plasmid studies of Salmonella typhimurium phage type 179 resistance to ampieillin, tetrneyeline, sulphonamides and trimethoprim. Journal of Hygiene 85, 293–300.CrossRefGoogle ScholarPubMed
Anderson, E. S. & Threlfall, E. J. (1984). The characterization of plasmids in the Enterobacteria. Journal of Hygiene 72, 471–487.CrossRefGoogle Scholar
Anderson, E. S., Threlfall, E. J., Carr, J. M., McConnell, M. M. & Smith, H. R. (1977). Clonal distribution of resistance plasmid-carrying Salmonella typhimurium, mainly in the Middle East. Journal of Hygiene 79, 425–448.CrossRefGoogle ScholarPubMed
Chugh, T. D. (1982). Plasmid-linked drug resistance in S. typhimurium in Kuwait. Antonie van Leeutvenhoek 48, 401–405.CrossRefGoogle Scholar
Chugh, T. D. & Bisrbishi, E. (1983). Trimethoprim R-plasmids in clinical isolates of salmonella in Kuwait. Proceedings of 13th International Congress of Chemotherapy, Vienna.Google Scholar
Chugh, T. D. & Kadri, M. H. (1984). Detection of R-plasmids in Salmonella isolated from clams and marine waters of Kuwait. Water, Air and Soil Pollution. (In the Press.)Google Scholar
Chugh, T. D., Suheir, A., Mahboob, A. G., Neil, L. & Bisrrishi, E. (1984). Plasmid mediated drug resistance of Shigellae in Kuwait. Antonie van Leeutvenhoek. (In the Press.)Google Scholar
Chun, D., Cho, D. K., Seol, S. Y., Suh, M. H. & Lee, Y. C. (1984). R-PIasmids conferring multiple drug resistance from Shigella isolated in Korea. Journal of Hygiene 92, 153–160.CrossRefGoogle ScholarPubMed
Datta, N. & Richards, H. (1981). Salmonella typhi in vivo acquires resistance to both chloramphenicol and cotrimoxazole. Lancel i, 1181–1183.CrossRefGoogle Scholar
Falbo, V., Caprioli, A., Nondella, F., Cacace, M. L., Luzi, S. & Greco, D. (1982). Antimicrobial resistance among salmonella isolates from hospitals in Rome. Journal of Hygiene 88, 275–284.CrossRefGoogle ScholarPubMed
Gross, R. J., Rowe, B., Cheasty, T. & Thomas, L. V. (1984). Increase in drug resistance among Sh. dysentcriae, Sh. flexneri and Sh. boydii. British Medical Journal 283, 575–576.CrossRefGoogle Scholar
Lopez-Brea, M., Callado, L., Vincente, F. & Perez-Diaz, J. C. (1983). Increasing antimicrobial resistance of Sh. sonnet. Journal of Antimicrobial Chemotherapy 11, 598–9.CrossRefGoogle Scholar
Rangnekar, V. M., Banker, D. D. & Jhala, H. I. (1983). Antimicrobial resistance and incompatibility groups of R-plasmids in S. typhimurium. Antimicrobial Agents and Chemotherapy 23, 54–58.CrossRefGoogle Scholar
Rowe, B. & Threlfall, E. J. (1981). Multiple antimicrobial drug resistance in enteric pathogens. Journal of Antimicrobial Chemotherapy 7, 1–3.CrossRefGoogle ScholarPubMed
Rowe, B., Frost, J. A., Threlfall, E. J. & Ward, L. D. (1980). Spread of a multircsistant clono of Salmonella typhimurium phage type 66/122 in South East Asia and the Middle East. Lancel, i 1070–1071.CrossRefGoogle Scholar
Threlfall, E. J., Frost, J. A., King, H. C. & Rowe, B. (1983). Plasmid-encoded trimethoprim resistance in salmonellas isolated in Britain between 1970 and 1981. Journal of Hygiene 90, 55–60.CrossRefGoogle ScholarPubMed
Towner, K. J., Pearson, N. J., Cattell, W. R. & O'Grady, F. (1978). Chromosomal resistance to trimethoprim. Lancel i, 1371–1372.CrossRefGoogle Scholar
Towner, K. J., Pearson, N. J.Pinn, P. A. & O'Grady, F. (1980). Increasing importance of plasmid-mediatcd trimethoprim resistance in entcrobactcria: two six-month surveys. British Medical Journal i, 517–519.CrossRefGoogle Scholar
Walia, S. K., Gupta, P. N., Arora, D. R. & Chugh, T. D. (1981). Trimcthoprimsulphamethoxazole resistance conferred by R-plasmids in clinical isolates of Salmonella typhimurium. Indian Journal of Medical Research 74, 631–634.Google Scholar