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Studies on the Inactivation of Complement by Shaking

Published online by Cambridge University Press:  15 May 2009

Hans Schmidt
Hans Schmidt
Affiliation:
(From the Bacteriological Department, Lister Institute, London.)
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In a former paper on the inactivation of the haemolytic complement by means of shaking (1913), I considered it possible that the process of shaking-inactivation might be explained by assuming that an adsorption of the complement occurred on the surfaces of the precipitate, which is always found when a serum is shaken. I was unable however either to fix the complement of a fresh serum by adding the centrifuged coagula of a shaken serum or, on the other hand, to set free a complement presumably adsorbed on the surface of precipitated proteins, which are found to be soluble only in alkali. I therefore had to leave undecided the question as regards the nature of the process of shaking-inactivation.

Type
Research Article
Information
Journal of Hygiene , Volume 14 , Issue 4 , December 1914 , pp. 417 - 436
Copyright
Copyright © Cambridge University Press 1914

References

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