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Studies on arboviruses in Egypt: II. Contribution of arboviruses to the aetiology of undiagnosed fever among children

Published online by Cambridge University Press:  15 May 2009

Y. S. Mohammed ,
M. Grešiková ,
K. Adamyová ,
A. H. Ragib  and
K. El-Dawala
Y. S. Mohammed
Affiliation:
Medical Research Institute, Hadara, Alexandria, Egypt and Institute of Virology, SAV, Bratislava, Czechoslovakia
M. Grešiková
Affiliation:
Medical Research Institute, Hadara, Alexandria, Egypt and Institute of Virology, SAV, Bratislava, Czechoslovakia
K. Adamyová
Affiliation:
Medical Research Institute, Hadara, Alexandria, Egypt and Institute of Virology, SAV, Bratislava, Czechoslovakia
A. H. Ragib
Affiliation:
Medical Research Institute, Hadara, Alexandria, Egypt and Institute of Virology, SAV, Bratislava, Czechoslovakia
K. El-Dawala
Affiliation:
Medical Research Institute, Hadara, Alexandria, Egypt and Institute of Virology, SAV, Bratislava, Czechoslovakia
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Acute blood samples from 120 children, attending the fever hospital in Alexandria and complaining of fever, were collected and examined for haemagglutination-inhibiting (HAI) and complement-fixing (CF) antibodies against the following arbovirus antigens; Sindbis, West Nile (WN), yellow fever, dengue 1, sandfly fever, Quaranfil, Chenuda and Nyamanini. Positive reactions in the acute sera were only detected against Sindbis (4·3%) and WN (4·3%) antigens. The convalescent sera obtained from 48 of these children showed a pronounced HAI titre against WN antigen in 14·6 % of them. The same sera showed a lower titre against yellow fever antigen (Asibi strain) which is due to cross-reaction between the two viruses. None of the acute or the convalescent sera showed CF antibodies against Quaranfil, Chenuda or Nyamanini antigens. The convalescent sera were not tested against dengue type 1 antigen. It is suggested that of the known arboviruses in Egypt, WN is the most important from the public health point of view.

Type
Research Article
Information
Journal of Hygiene , Volume 68 , Issue 3 , September 1970 , pp. 491 - 495
Copyright
Copyright © Cambridge University Press 1970

References

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