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The routine serological investigation of cases and contacts of rubella

Published online by Cambridge University Press:  15 May 2009

J. R. Pattison  and
D. S. Dane
J. R. Pattison
Affiliation:
Department of Virology, London Hospital Medical College, Turner Street, London E1 2AD
D. S. Dane
Affiliation:
Department of Virology, Middlesex Hospital Medical School, Riding House Street, London W1
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Summary

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The results of testing sera from 111 patients with rubella-like illnesses and 283 contacts of patients with rubella-like illnesses are described. A sensitive haemagglutination-inhibition test was used in conjunction with fractionation of serum proteins when this was indicated. It was concluded that the testing of serum protein fractions for IgM and IgG rubella antibody greatly increased the effectiveness of laboratory diagnosis. Evidence is presented that during the study period subclinical rubella was relatively uncommon in adults and that the accuracy of clinical diagnosis was high.

Type
Research Article
Information
Journal of Hygiene , Volume 75 , Issue 1 , August 1975 , pp. 91 - 98
Copyright
Copyright © Cambridge University Press 1975

References

REFERENCES

Brody, J. A. (1966). The infectiousness of rubella and the possibility of reinfection. American Journal of Public Health 56, 1082.CrossRefGoogle ScholarPubMed
Emond, R. T. D. (1971). Rubella. British Journal of Hospital Medicine 5, 313.Google Scholar
Forbes, J. A. (1969). Rubella: historical aspects. American Journal of Diseases of Children 118, 5.Google ScholarPubMed
Haire, M. & Hadden, D. S. M. (1972). Rapid diagnosis of rubella by direct immunofluorescent staining of desquamated cells in throat swabs. Journal of Medical Microbiology 5, 231.CrossRefGoogle ScholarPubMed
Pattison, J. R. & Mace, J. E. (1973). A simple gel filtration technique for use in diagnostic serology. Journal of Clinical Pathology 26, 309.CrossRefGoogle ScholarPubMed
Pattison, J. R. & Mace, J. E. (1975). The detection of specific IgM antibodies following infection with rubella virus. Journal of Clinical Pathology 28, 377.Google Scholar
Peckham, C. S. (1974). Clinical and serological assessment of children exposed in utero to confirmed maternal rubella. British Medical Journal i, 259.Google Scholar
Report of the P.H.L.S. Rubella Working Party (1968). Studies on rubella in pregnancy. British Medical Journal iii, 203.Google Scholar