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Prevalence of cytomegalovirus in France*

Published online by Cambridge University Press:  15 May 2009

M. Jeddi
Affiliation:
Section de Virologie du Laboratoire National de la Santé Publique, 8, Avenue Rockefeller, Lyon 8e, France
O. G. Gaudin
Affiliation:
Section de Virologie du Laboratoire National de la Santé Publique, 8, Avenue Rockefeller, Lyon 8e, France
R. Sohier
Affiliation:
Section de Virologie du Laboratoire National de la Santé Publique, 8, Avenue Rockefeller, Lyon 8e, France
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Summary

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Between October 1968 and February 1970, 30 strains of cytomegalovirus were isolated from the urine of children admitted to hospitals in Lyon. Three groups of children up to the age of 14 years have been investigated.

The first group consisted of 304 newborns and infants up to the age of 1 year; cytomegalovirus was grown from five of these (1·6%). Among these five children, two had cerebral disorders. None of them had ever shown any sign of typical CMV infection.

The second group comprised 102 children between the ages of 1 and 14 years, from a special service for neurological and mental diseases. Cytomegalovirus was grown from 19 (18·6%).

The third group was 27 children also between 1 and 14 years of age, admitted to hospital for miscellaneous diseases excluding cerebral disorders; cytomegalovirus was grown from six (22·2%).

It appears that cytomegalovirus has a very low incidence in neonatal disease. The virus spreads at a higher rate in children 1–14 years old. No difference has so far been shown in the excretion rates of two groups of children, one with cerebral disorders and one with other diseases, but the number of children in the last group is too small to allow definite conclusions to be drawn.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1971

References

REFERENCES

Cherry, J. D., Soriano, F., Jahn, C. L. & Wis, M. (1968). Search for perinatal viral infection. American Journal of Diseases of Children 116, 245–50.Google Scholar
Chiba, S., Osaki, M., Hanazono, H. & Nakao, T. (1968). Cytomegalovirus infection in children in Japan. Japanese Journal of Microbiology 12, 489–94.CrossRefGoogle ScholarPubMed
Crome, L. & France, N. E. (1959). Microgyria and cytomegalic inclusion disease in infancy. Journal of Clinical Pathology 12, 427–34.CrossRefGoogle ScholarPubMed
De Fouquet, J. M. (1956). Les lésions cérébrales de la maladie généralisée des inclusions cytomégaliques. Thèse Med., Paris.Google Scholar
Feldman, R. A. (1969). Cytomegalovirus infection during pregnancy. A prospective study and report of six cases. American Journal of Diseases of Children 117, 517–21.CrossRefGoogle ScholarPubMed
Hanshaw, J. B. (1966). Cytomegalovirus complement-fixing antibody in microcephaly. New England Journal of Medicine 275, 476–9.CrossRefGoogle ScholarPubMed
Jeddi, M., Gaudin, O. G., Terraillon, J. & Sohier, R. (1969). Recherche de la fréquence et de la répartition de l'infection à virus cytomégalique dans la région lyonnaise. (Enquête sérologique préliminaire par la réaction de fixation du complément.) Bulletin de l' Académie Nationale de Médicine 153, 318–21.Google Scholar
Krech, U., Jung, M., Bärlocher, K. & Sege, L. (1968). Incidence of intrauterine cyto-megalovirus infections. German Medical Monthly 13, 184–90.Google Scholar
Li, F. & Hanshaw, J. B. (1967). Cytomegalovirus infection among migrant children. American Journal of Epidemiology 86, 137–41.CrossRefGoogle ScholarPubMed
Marie, J., Sée, G., Grüner, J., Hébert, S., De Gennes, J. L. & De Fouquet, J. (1957). Manifestations cérébrales de la maladie des inclusions cytomégaliques. Semaine des Hôpitaux de Paris, Annales de Pédiatrie 33, 1614–22.Google Scholar
Nezelof, C., Gaquière, A. & Brousse, A. (1961). Les inclusions cytomégaliques chez l'adulte. Première observation française et revue de la littérature. Presse Médicale 69, 1845–8.Google Scholar
Sanders, D. Y. & Cramblett, H. G. (1968). Viral infections in hospitalized neonates. American Journal of Diseases of Children 116, 251–6.Google ScholarPubMed
Starr, J. G. & Gold, E. (1968). Screening of newborn infants for Cytomegalovirus infection. Journal of Pediatrics 73, 820–4.Google Scholar
Stern, H. (1968). Isolation of Cytomegalovirus and clinical manifestation of infection at different ages. British Medical Journal i, 665–9.Google Scholar
Stern, H., Elek, S. D., Booth, J. C. & Fleck, D. G. (1969). Microbial causes of mental retardation. The role of prenatal infections with Cytomegalovirus, rubella virus and toxoplasma. Lancet ii, 443–8.Google Scholar