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The Precipitation Reaction: Optimal Proportions, Neutrality and Maximal Precipitation in Mixtures of Albumin and Antiserum

Published online by Cambridge University Press:  15 May 2009

G. L. Taylor
Affiliation:
From the Department of Pathology, the Low Temperature Station and the Biochemical Laboratory, Cambridge.
G. S. Adair
Affiliation:
From the Department of Pathology, theLow Temperature Station and the Biochemical Laboratory, Cambridge.
Muriel E. Adair
Affiliation:
From the Department of Pathology, theLow Temperature Station and the Biochemical Laboratory, Cambridge.
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Culbertson (1932) has recently described a method for estimating the antibody content of antisera against crystalline egg-albumin. He determined by tests on supernatant fluids the point at which antigen and antibody neutralised each other. At this neutralisation point he found that antigen and antibody combined in a ratio of 1 to 13, and that the amount of precipitate nitrogen was maximal. The ratio 1 to 13, he stated, held for all the precipitates in the post-zone where antibody was in excess.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1934

References

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