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Plasmid content and protein I serovar of non-pencillinase-producing gonococci isolated in Munich

Published online by Cambridge University Press:  19 October 2009

D. Abeck ,
A. P. Johnson ,
F. E. Alexander ,
H. C. Korting  and
D. Taylor-Robinson
D. Abeck
Affiliation:
Division of Sexually Transmitted Diseases, MRC Clinical Research Centre, Harrow, Middlesex, HA1 3UJ Department of Dermatology, Ludwig-Maximilians Universität, Munich, FRG
A. P. Johnson
Affiliation:
Division of Sexually Transmitted Diseases, MRC Clinical Research Centre, Harrow, Middlesex, HA1 3UJ
F. E. Alexander
Affiliation:
Division of Sexually Transmitted Diseases, MRC Clinical Research Centre, Harrow, Middlesex, HA1 3UJ
H. C. Korting
Affiliation:
Department of Dermatology, Ludwig-Maximilians Universität, Munich, FRG
D. Taylor-Robinson
Affiliation:
Division of Sexually Transmitted Diseases, MRC Clinical Research Centre, Harrow, Middlesex, HA1 3UJ
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One hundred and twenty-four strains of non-penicillinase-producing gonococci isolated in Munich in 1986 were characterized in terms of their plasmid content and protein I serovar. Eighty-two per cent of the strains belonged to serogroup 1-B with over half belonging to either serovar 1B-2 or 1B-3. Half of the 22 serogroup 1A strains belonged to serovar 1A-2. Nineteen strains (15·3%) were found to lack the 2·6 Md cryptic plasmid although seven of these strains contained the 24·4 Md conjugative plasmid. Nine of the 105 strains which harboured the cryptic plasmid also contained the conjugative plasmid. The 19 strains which lacked the cryptic plasmid comprised 10 different serovars, indicating the heterogeneous nature of this group of organisms.

Type
Research Article
Information
Epidemiology & Infection , Volume 100 , Issue 3 , June 1988 , pp. 345 - 349
Copyright
Copyright © Cambridge University Press 1988

References

Abeck, D., Johnson, A. P. & Korting, H. C. (1987). Characterisation of penicillinaseproducing gonococci isolated in Munich, 1981–1986. Genitourinary Medicine 64, 3–6.Google Scholar
Bibnboim, H. C. & Doly, J. A. (1979). A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acid Research 7, 1513–23.Google Scholar
Catlin, B. W. (1973). Nutritional profiles for Neisseria gonorrhoeae, Neisseria meningitidis and Neisseria lactamica in chemically defined media and the use of growth requirements for gonococcal typing. Journal of Infectious Diseases 128, 178–94.Google Scholar
Dillon, J. R., Bygdeman, S. M. & Sandstrom, E. G. (1987). Serological ecology of Neisseria gonorrhoeae (PPNG and non-PPNG) strains: Canadian perspective. Genitourinary Medicine 63, 160–8.Google Scholar
Handsfield, H. H., Sandstrom, E. G., Knapp, J. S., Perine, P. L., Whittington, W. L., Sayers, D. E. & Holmes, K. K. (1982). Epidemiology of penicillinase-producing Neisseria gonorrhoeae infections. Analysis by auxotyping and serogrouping. New England Journal of Medicine 306, 950–954.CrossRefGoogle ScholarPubMed
Knapp, J. S., Tam, M. R., Nowinski, R. C., Holmes, K. K. & Sandstrom, E.G. (1984). Serological classification of Neisseria gonorrhoeae with use of monoclonal antibodies to gonococcal outer membrane protein I. Journal of Infectious Diseases 150, 44–48.CrossRefGoogle ScholarPubMed
Kohl, P. A., Knapp, J. S., Hoffman, H., Gruender, K., Petzoldt, D., Tams, M. R. & Holmes, K. K. (1986). Epidemiological analysis of Neisseria gonorrhoeae in the Federal Republic of Germany by auxotyping and serological classification using monoclonal antibodies. Genitourinary Medicine 62, 145–50.Google Scholar
Perine, P. L., Thornsberry, C., Schalla, W., Biddle, J., Siegel, M. S., Wong, K.-H. & Thompson, S. E. (1977). Evidence for two distinct types of penicillinase-producing Neisseria gonorrhoeae. Lancet ii, 993–995.Google Scholar
Ramstedt, K. M., Hallhagen, G. J., Bygdeman, S. M., Lincoln, K. A., Kallings, I., Gillenius, C. & Sandström, E. G. (1985). Serologic classification and contact tracing in the control of microepidemics of β-lactamase-producing Neisseria gonorrhoeae. Sexually Transmitted Diseases 12, 209–214.Google Scholar
Roberts, M., Piot, P. & Falkow, S. (1979). The ecology of gonococcal plasmids. Journal of General Microbiology 114, 491–4.CrossRefGoogle ScholarPubMed