On Variation in Weight of Normal Guinea-pigs in relation to the Estimation of Free Diphtheria Toxin

Extract

In the foregoing paper (p. 512) relationships have been established between loss of weight in test guinea-pigs and dose of diphtheria toxin injected. In connection with the above, the normal increase of weight during the period of observation, the effect of the animal ceasing to eat, or any change of diet, had to be taken into consideration. The following note records observations on normal increase of weight, with constant and variable diet, on healthy animals.