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Occurrence of FIme plasmids in multiply antimicrobial-resistant Escherichia coli isolated from urinary tract infection

Published online by Cambridge University Press:  15 May 2009

P. A. Riley ,
E. J. Threlfall ,
T. Cheasty ,
K. G. Wooldridge ,
P. H. Williams  and
I. Phillips
P. A. Riley
Affiliation:
Department of Microbiology, United Medical and Dental Schools, St Thomas's Hospital, London SE1 7EH
E. J. Threlfall
Affiliation:
Laboratory of Enteric Pathogens, Central Public Health Laboratory, 6I Colindale Avenue, London NW9 5HT
T. Cheasty
Affiliation:
Laboratory of Enteric Pathogens, Central Public Health Laboratory, 6I Colindale Avenue, London NW9 5HT
K. G. Wooldridge
Affiliation:
Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH
P. H. Williams
Affiliation:
Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH
I. Phillips
Affiliation:
Department of Microbiology, United Medical and Dental Schools, St Thomas's Hospital, London SE1 7EH
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Plasmids belonging to the FIme incompatibility group were found in seven different serogroups of multiply antimicrobial-resistant Escherichia coli isolated from patients with urinary tract infection (UTI) and living in south-east London. Although widespread in Salmonella spp., FIme plasmids have only previously been described in E. coli in a strain of serogroup O15 K52 H1 responsible for an extensive and protracted outbreak of invasive community-acquired infection in south-east London in 1986. Our findings suggest either a wider background occurrence of FIme plasmids in E. coli associated with UTI than previously reported or alternatively, the dissemination and subsequent molecular diversification of the FIme plasmid associated with the epidemic strain of serogroup O15 K52 H1.

Type
Research Article
Information
Epidemiology & Infection , Volume 110 , Issue 3 , June 1993 , pp. 459 - 468
Copyright
Copyright © Cambridge University Press 1993

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